Related Experiment Video
Updated: May 28, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
Published on: July 5, 2021
Diagnosis and endoscopic management of sinonasal schwannomas
Jeffrey D Suh1, Vijay R Ramakrishnan, Paul J Zhang
1Division of Head and Neck Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. jeffsuh@mednet.ucla.edu
Aims:
Survey the clinical symptoms, radiological features, management, and long-term outcomes of sinonasal and anterior skull base schwannomas.
Patients And Methods:
Retrospective review of patients with sinonasal schwannomas treated from June 2001 through January 2010 at two academic institutions.
Results:
There were 4 women and 3 men in this study. The mean age was 46 years (range 17-68). The mean tumor size was 2.4 cm (range 1.4-3.8 cm). Tumor locations included ethmoid sinuses (3), nasal cavity (2) and pterygopalatine fossa (2). Six patients had endoscopic resections, while 1 was approached and resected via a lateral rhinotomy. The mean follow-up was 2.8 years. There were no tumor recurrences during the study period.
Conclusions:
Schwannomas of the paranasal sinuses and nasal cavity are uncommon tumors that can usually present with vague and nonspecific symptoms. Magnetic resonance imaging can suggest the diagnosis; however, a definitive diagnosis is made by correlation with histopathological findings. Treatment is complete surgical resection. This study illustrates the effectiveness of the endoscopic endonasal approach in the treatment of these benign tumors.
