Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 28, 2026

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models
08:57

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models

Published on: May 17, 2024

Primary pancreatic pleomorphic leiomyosarcoma.

Q-Y Zhang1, Q-Y Shen, S Yan

  • 1Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.

The Journal of International Medical Research
|October 12, 2011
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Ex vivo liver resection with autotransplantation for initially unresectable colorectal liver metastases: a systematic review].

Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery·2026
Same author

[Etiological characteristics of hand, foot and mouth disease in Henan Province, 2021-2024].

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi·2026
Same author

Evidence for the Collective Nature of Radial Flow in Pb+Pb Collisions with the ATLAS Detector.

Physical review letters·2026
Same author

Evidence for the Dimuon Decay of the Higgs Boson in pp Collisions with the ATLAS Detector.

Physical review letters·2025
Same author

[Renal response and prognosis of newly diagnosed patients with multiple myeloma with renal impairment applying VRD and autologous hematopoietic stem cell transplantation].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi·2025
Same author

Evidence for Longitudinally Polarized W Bosons in the Electroweak Production of Same-Sign W Boson Pairs in Association with Two Jets in pp Collisions at sqrt[s]=13  TeV with the ATLAS Detector.

Physical review letters·2025
Same journal

Clinical efficacy and electromyographic analysis of direct current hydrotherapy in the treatment of upper limb peripheral nerve injuries: A randomized controlled trial.

The Journal of international medical research·2026
Same journal

Tacrolimus intrapatient variability and latent virus reactivation after kidney transplantation: A retrospective study comparing prolonged-release and immediate-release tacrolimus formulations.

The Journal of international medical research·2026
Same journal

Dexmedetomidine for the prevention of postoperative atrial fibrillation: A systematic review and meta-analysis.

The Journal of international medical research·2026
Same journal

Causal effects of blood and urinary biomarkers on cancer risk: A Mendelian randomization study.

The Journal of international medical research·2026
Same journal

Autophagy-related pathway dysregulation and apoptosis suppression in pterygium: Role of key biomarkers Beclin-1, ATG5, LC3, p62, and Bcl-2 in pathogenesis and potential nonsurgical targets.

The Journal of international medical research·2026
Same journal

Clinical efficacy and safety of icodextrin dialysate for overnight dwell in continuous ambulatory peritoneal dialysis: A prospective self-controlled study.

The Journal of international medical research·2026
See all related articles

Primary pancreatic leiomyosarcoma, a rare smooth muscle tumor, was diagnosed in a 56-year-old female. Radical surgical resection led to a tumor-free outcome 14 months post-operation, highlighting its importance for survival.

Area of Science:

  • Oncology
  • Gastroenterology
  • Pathology

Background:

  • Primary pancreatic leiomyosarcoma is a rare mesenchymal neoplasm originating from pancreatic vasculature or ducts.
  • This tumor type is exceptionally uncommon, necessitating detailed diagnostic approaches.

Observation:

  • A 56-year-old female presented with epigastric pain and an abdominal mass.
  • Computed tomography revealed a large soft tissue mass in the pancreatic body and tail.
  • Fine needle aspiration biopsy suggested a spindle cell tumor.

Findings:

  • Histological examination confirmed a pleomorphic spindle cell neoplasm with smooth muscle differentiation.
  • Immunohistochemical analysis supported the diagnosis of primary pleomorphic leiomyosarcoma.
  • The patient underwent distal pancreatectomy without adjuvant therapy.

Related Experiment Videos

Last Updated: May 28, 2026

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models
08:57

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models

Published on: May 17, 2024

Implications:

  • Radical surgical resection is crucial for achieving long-term survival in patients with primary pancreatic leiomyosarcoma.
  • Immunohistochemical analysis is essential for accurate diagnosis of this highly malignant tumor.
  • Complete surgical removal offers the only chance for long-term patient survival.