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Updated: May 28, 2026

Scalable 96-well Plate Based iPSC Culture and Production Using a Robotic Liquid Handling System
Published on: May 14, 2015
Introduction to induced pluripotent stem cells: advancing the potential for personalized medicine
Johnathan D Ebben1, Michael Zorniak, Paul A Clark
1Brain Tumor Research Laboratory, Department of Neurological Surgery, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, USA.
None:
Induced pluripotent stem (iPS) cell technology has enormous potential to advance medical therapy by personalizing regenerative medicine and creating novel human disease models for research and therapeutic testing. Before this technology is broadly used in the clinic, we must realistically evaluate its disease modeling and therapeutic potential. Recent advances including the use of iPS cells to successfully model spinal muscular atrophy in vitro, as well as new techniques in generating iPS cells with recombinant proteins have accelerated the prospects of iPS cells for clinical use in regenerative therapy. This review explores the development and limitations of iPS cell technology, presents a critical comparison of iPS cells and embryonic stem cells, and discusses potential clinical applications and future research directions.
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