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Related Concept Videos

Bone Markings01:26

Bone Markings

Bones have various surface features that help form joints and attach to other soft tissues. Depending on the function, bone markings are categorized into articulating projections, processes for attachment, depressions, and openings.
Articulating Projections
Articulating projections are found where two bones meet to form a joint. These structures are usually found at the ends of bones. The largest articulation is a rounded projection called the head, supported by a narrow neck at the ends of...
Cranial Bones: Lateral View01:27

Cranial Bones: Lateral View

The lateral view of the cranium is dominated by temporal, sphenoid, and ethmoid bones.
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
Bone Formation by Intramembranous Ossification01:29

Bone Formation by Intramembranous Ossification

Intramembranous ossification is one of the two processes involved in the development of bones within an embryo. The flat bones of the face, most of the cranial bones, and the clavicles are formed via this process. During intramembranous ossification, the bones develop directly from sheets of undifferentiated mesenchymal connective tissue.
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into...
Anatomy of the Brain: Ventricles01:18

Anatomy of the Brain: Ventricles

There are hollow fluid-filled cavities known as ventricles deep inside the human brain. There are two lateral ventricles, one in each cerebral hemisphere, and each has three different projections — the anterior, inferior, and posterior horns visible from the lateral side. A thin membrane called the septum pellucidum separates the two lateral ventricles. The slender third ventricle in the diencephalon is connected to each lateral ventricle via a channel called the interventricular foramen. The...
Gross Anatomy of Bone01:17

Gross Anatomy of Bone

The two main features of a long bone are the diaphysis and the epiphysis.
The diaphysis is the tubular shaft that runs between the proximal and distal ends of the bone. The walls of the diaphysis are composed of dense and hard compact bone made of numerous osteons — the functional unit of the compact bone. The hollow region in the diaphysis is called the medullary cavity, which harbors the bone marrow. In infants and children, this marrow cavity is filled with red marrow, whereas in adults, it...
Bone Formation by Endochondral Ossification01:24

Bone Formation by Endochondral Ossification

Bone formation, or ossification, begins around the sixth to seventh week of embryonic development. Most bones develop from a cartilaginous template through the process of endochondral ossification. Cartilage formation begins when clusters of mesenchymal cells differentiate into chondrocytes. These chondrocytes proliferate rapidly and secrete an extracellular matrix that becomes encased in a membrane called the perichondrium. The resulting cartilage model provides a template that resembles the...

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Related Experiment Video

Updated: May 28, 2026

Visualization of Chondrocyte Intercalation and Directional Proliferation via Zebrabow Clonal Cell Analysis in the Embryonic Meckel’s Cartilage
06:40

Visualization of Chondrocyte Intercalation and Directional Proliferation via Zebrabow Clonal Cell Analysis in the Embryonic Meckel’s Cartilage

Published on: October 21, 2015

Meckel's cave.

Pulat Akın Sabancı1, Funda Batay, Erdinç Civelek

  • 1Department of Neurosurgery, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey. sabanci.akin@gmail.com

World Neurosurgery
|October 12, 2011
PubMed
Summary
This summary is machine-generated.

Understanding the microsurgical anatomy of Meckel's cave is crucial for neurosurgeons. This study details its complex structure to improve surgical strategies and orientation in the middle cranial fossa.

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Visualization of Chondrocyte Intercalation and Directional Proliferation via Zebrabow Clonal Cell Analysis in the Embryonic Meckel’s Cartilage
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An Explant Assay for Assessing Cellular Behavior of the Cranial Mesenchyme
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Published on: January 20, 2013

Area of Science:

  • Neurosurgery
  • Anatomy
  • Microsurgery

Background:

  • Meckel's cave is a critical anatomical space in the middle cranial fossa.
  • Precise knowledge of its microsurgical anatomy is essential for successful surgical interventions.

Purpose of the Study:

  • To delineate the microsurgical anatomy of Meckel's cave.
  • To provide anatomical data for improved surgical planning and execution in this region.

Main Methods:

  • Microsurgical dissection of Meckel's cave in 15 human cadaver heads (30 sides).
  • Histological examination of serial sections from an additional cadaver specimen to understand meningeal and cross-sectional anatomy.

Main Results:

  • Meckel's cave is an aperture in the middle cranial fossa housing the trigeminal nerve rootlets and ganglion.
  • Detailed measurements of the cave's dimensions and its relation to surrounding neurovascular structures were recorded.
  • The cave's average height was 4.2 mm and width 7.6 mm, with specific distances noted to the internal acoustic meatus and arcuate eminence.

Conclusions:

  • A thorough understanding of Meckel's cave microsurgical anatomy is vital for precise microneurosurgery.
  • This anatomical knowledge aids in developing comprehensive surgical strategies and maintaining accurate orientation.
  • The study provides essential anatomical insights for neurosurgeons operating near the internal carotid artery and cavernous sinus.