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Related Experiment Video

Updated: May 28, 2026

Disruption of the Mouse Blood-Brain Barrier by Small Extracellular Vesicles from Hypoxic Human Placentas

Disruption of the Mouse Blood-Brain Barrier by Small Extracellular Vesicles from Hypoxic Human Placentas

Published on: January 26, 2024

Maternal cardiac function in preeclampsia.

Karen Melchiorre¹, Basky Thilaganathan

¹Department of Obstetrics and Gynecology, Fetal Maternal Medicine Unit, St Georges Hospital, University of London, London, UK.

Current Opinion in Obstetrics & Gynecology

|October 12, 2011

Summary

This summary is machine-generated.

Preeclampsia significantly increases cardiovascular risk, leading to asymptomatic heart dysfunction and hypertension postpartum. Early-onset preeclampsia is particularly linked to long-term heart health issues.

Related Experiment Videos

Last Updated: May 28, 2026

Disruption of the Mouse Blood-Brain Barrier by Small Extracellular Vesicles from Hypoxic Human Placentas

Disruption of the Mouse Blood-Brain Barrier by Small Extracellular Vesicles from Hypoxic Human Placentas

Published on: January 26, 2024

Area of Science:

Cardiology
Obstetrics
Reproductive Medicine

Background:

Preeclampsia is linked to acute cardiovascular complications and long-term cardiovascular disease.
It can acutely impair cardiac function, cause myocardial ischemia, and affect long-term heart health.

Purpose of the Study:

To review recent insights into cardiovascular impairment in preeclampsia and postpartum.
To highlight the association between preeclampsia and subsequent cardiovascular morbidity and mortality.

Main Methods:

Utilized newer, sensitive echocardiographic indices to detect asymptomatic myocardial damage.
Correlated findings with invasive indices of myocardial function.
Assessed predictive value for subsequent cardiovascular morbidity.

Main Results:

Found a high prevalence of cardiac impairment in preeclampsia and postpartum.
Detected asymptomatic left ventricular dysfunction/hypertrophy (Stage B heart failure).
Observed increased prevalence of hypertension and cardiovascular risk postpartum, especially with early-onset preeclampsia.

Conclusions:

Preeclampsia, particularly early-onset, is associated with significant long-term cardiovascular risk.
History of early-onset preeclampsia identifies women at high cardiovascular risk, even without other risk factors.
Findings underscore the importance of monitoring cardiovascular health in women with a history of preeclampsia.