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Updated: May 28, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
09:21

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

Optimizing the Hachinski Ischemic Scale.

Vladimir Hachinski1, Shahram Oveisgharan, A Kimball Romney

  • 1Department of Clinical Neurological Sciences, University Hospital, University of Western Ontario, London, Ontario, Canada. vladimir.hachinski@lhsc.on.ca

Archives of Neurology
|October 12, 2011
PubMed
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The Hachinski Ischemic Score (HIS) was optimized, yielding 5-item and 7-item versions. These reduced HIS versions accurately diagnose vascular dementia, performing as well as or better than the original 13-item HIS.

Area of Science:

  • Gerontology
  • Neurology
  • Epidemiology

Background:

  • Vascular factors are a significant, preventable cause of cognitive disorders in the elderly.
  • The Hachinski Ischemic Score (HIS) is widely used for diagnosing vascular dementia.

Purpose of the Study:

  • To consolidate and validate the Hachinski Ischemic Score (HIS).
  • To identify optimal scaling and a minimal set of HIS items for improved variance explanation.

Main Methods:

  • Utilized data from the Canadian Study for Health and Aging (CSHA) cohort study (1991-2002).
  • Applied correspondence analysis to a 13-item HIS from 2968 participants in CSHA phases 2 and 3.
  • Identified optimal item sets and scoring for HIS validation.

Main Results:

Related Experiment Videos

Last Updated: May 28, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
09:21

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

  • Two optimized HIS versions (5-item and 7-item) were developed.
  • The 7-item HIS, using binary scoring, performed comparably to the original 13-item HIS.
  • A 5-item composite HIS model demonstrated improved classification of vascular vs. nonvascular dementia.

Conclusions:

  • Reduced HIS versions (5-item composite or 7-item single-question) offer comparable or superior diagnostic accuracy.
  • These optimized HIS versions provide flexibility for different clinical settings.
  • The study validates and refines the HIS for diagnosing vascular dementia.