A new benzodioxocinone from the leaves of Cinnamomum tenuifolium
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Published on: February 2, 2024
Hsin-Liang Chen1, Soong-Yu Kuo, Yun-Ping Li
1School of Medical and Health Sciences, Fooyin University, Kaohsiung County, Taiwan, ROC.
Abstract:
Investigation of the leaves' extract of Cinnamomum tenuifolium (Lauraceae) led to the isolation of one novel benzodioxocinone, 2,3-dihydro-6,6-dimethylbenzo-[b][1,5]dioxocin-4(6 H)-one (1). The structure was determined through in-depth spectroscopic and mass-spectrometric analyses. The antioxidant potential was evaluated using the following in vitro method: scavenging of 1,1-diphenyl-2-picrylhydrazyl radical. We also detected the anti-proliferative effect of 1 on human oral cancer cells and its IC(50) is 107.7 µM.
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