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Updated: May 28, 2026

Particle Agglutination Method for Poliovirus Identification
Published on: April 20, 2011
Mucosal immunity to poliovirus
Pearay L Ogra1, Hiromasa Okayasu, Cecil Czerkinsky
1State University of New York, Women and Children's Hospital, 219 Bryant Street, Buffalo, NY 14222, USA.
Abstract:
The Global Polio Eradication Initiative (GPEI) currently based on use of oral poliovirus vaccine (OPV) has identified suboptimal immunogenicity of this vaccine as a major impediment to eradication, with a failure to induce protection against paralytic poliomyelitis in certain population segments in some parts of the world. The Mucosal Immunity and Poliovirus Vaccines: Impact on Wild Poliovirus Infection, Transmission and Vaccine Failure conference was organized to obtain a better understanding of the current status of global control of poliomyelitis and identify approaches to improve the immune responsiveness and effectiveness of the orally administered poliovirus vaccines in order to accelerate the global eradication of paralytic poliomyelitis.
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