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Related Experiment Videos

Anaesthesia, movement and emesis.

B Kamath1, J Curran, C Hawkey

  • 1Department of Anaesthesia, City Hospital and Queen's Medical Centre, Nottingham.

British Journal of Anaesthesia
|June 1, 1990
PubMed
Summary
This summary is machine-generated.

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Temazepam premedication significantly reduced postoperative nausea in women undergoing dilatation and curettage. Pre-existing motion sickness susceptibility may help identify patients at higher risk for nausea.

Area of Science:

  • Anesthesiology
  • Pharmacology
  • Gynecology

Background:

  • Postoperative nausea and vomiting (PONV) is a common complication following gynecological procedures.
  • Dilatation and curettage (D&C) is a frequently performed gynecological surgery with a risk of PONV.
  • Effective premedication strategies are crucial for managing PONV.

Purpose of the Study:

  • To evaluate the efficacy of temazepam and papaveretum-hyoscine premedication in reducing postoperative nausea after dilatation and curettage.
  • To identify factors associated with postoperative nausea in patients undergoing D&C.

Main Methods:

  • A randomized controlled trial involving 182 women undergoing D&C.
  • Patients were randomly assigned to receive premedication with temazepam, papaveretum-hyoscine, or placebo.

Related Experiment Videos

  • Postoperative nausea episodes and contributing factors were assessed.

    • Main Results:

    • Temazepam significantly reduced the incidence of postoperative nausea compared to placebo.
    • Sixty-six percent of patients who experienced nausea identified movement as a contributing factor.
    • Patients reporting nausea had higher motion sickness susceptibility scores and a history of prior nausea/vomiting treatment.

    Conclusions:

    • Temazepam is an effective premedication for reducing postoperative nausea following D&C.
    • Motion sickness susceptibility and previous treatment history are indicators for identifying patients at risk of PONV.
    • Preoperative identification of susceptible patients may allow for targeted PONV prophylaxis.