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Updated: May 28, 2026

Detrusor Underactivity Model in Rats by Conus Medullaris Transection
Published on: August 28, 2020
Symptom-based diagnosis of overactive bladder: an overview
1Division of Urology, University of Pennsylvania School of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA.
Abstract:
The current definition of overactive bladder (OAB) is "urgency, with or without urge incontinence, usually with frequency and nocturia in the absence of an underlying metabolic or pathologic condition." Urgency, in turn, is defined as a "sudden, compelling desire to pass urine that is difficult to defer." While these definitions provide the framework for making a clinical diagnosis of OAB, they rely on subjective assessment of the symptoms by the patient. As well, the symptoms of OAB can be similar to those seen in other conditions, such as urinary tract infection, benign prostatic enlargement and bladder cancer. These other potential diagnoses should be ruled out in a noninvasive manner before making a diagnosis of OAB.
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