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Middle Cerebral Artery Occlusion Allowing Reperfusion via Common Carotid Artery Repair in Mice
Published on: January 23, 2019
Use of far field basilar artery stenting for recurrent middle cerebral artery ischemia
W Lee Titsworth1, A Cahid Civelek, Alex Abou-Chebl
1Department of Anatomical Sciences and Neurobiology, University of Louisville School of Medicine, Louisville, Kentucky, USA.
Insights
Basilar artery stenting improved collateral flow, preventing recurrent middle cerebral artery strokes in a patient with internal carotid artery occlusion. This far-field intervention offers a safe option for stroke prevention when other treatments fail.
Area of Science:
- Neurology
- Interventional Neuroradiology
- Vascular Surgery
Background:
- Intracranial angioplasty and stenting are standard for stroke prevention in stenotic disease.
- Limited options exist for chronic proximal feeding vessel occlusion.
- Improving collateral flow is crucial in complex cerebrovascular cases.
Observation:
- A case study involving a patient with recurrent middle cerebral artery (MCA) strokes due to internal carotid artery occlusion.
- The patient had undergone a superior temporal artery (STA)-MCA bypass without complete resolution of symptoms.
- Basilar artery (BA) stenting was performed to enhance collateral circulation.
Findings:
- Basilar artery stenting led to complete cessation of MCA ischemia.
- Cerebrovascular reserve improved significantly, as evidenced by single-photon emission CT.
- The procedure was deemed safe and effective in mitigating recurrent MCA infarctions.
Implications:
- Far-field intracranial angioplasty and stenting can be a viable strategy for improving collateral flow.
- This approach should be considered for selected patients with chronic occlusive cerebrovascular disease who have failed other treatments.
- It expands therapeutic options for complex stroke prevention.
Abstract:
Intracranial artery angioplasty and stenting are generally performed for ipsi-territory stroke prevention in stenotic disease; however, few options exist for chronic occlusion of a proximal feeding vessel. In such circumstances intracranial angioplasty and stenting of a neighboring vascular field may improve collateral flow to the territory of the occluded vessel. A case of basilar artery (BA) stenting is presented, performed to improve collateral flow in a man experiencing recurrent middle cerebral artery (MCA) strokes, despite superior temporal artery (STA)-MCA bypass for internal carotid artery occlusion. Following BA stenting, the patient had complete cessation of MCA ischemia and improved cerebrovascular reserve by single photon emission CT. BA stenting was found to be a safe and effective means of improving collateral flow to mitigate recurrent MCA infarctions. Far field interventions should be considered in selected patients who fail other treatments.
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