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Related Concept Videos

Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic01:26

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic

Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies. Common...
Pneumonia I: Introduction01:29

Pneumonia I: Introduction

Pneumonia is an infection of the lower respiratory tract that leads to inflammation of the lung parenchyma, often resulting in the accumulation of inflammatory exudate in the alveoli and airways. Unlike the watery, low-protein fluid exudate in pulmonary edema, the exudate in this case is a thick fluid rich in immune cells, proteins, and debris produced during infection and inflammation.This impairs gas exchange and can lead to consolidation of lung tissue. The infection may be caused by a...
Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
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Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications01:25

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications

Peritoneal dialysis (PD) is a medical process that removes waste products and excess fluid from the body using the peritoneal membrane as a natural filter.Peritoneal Dialysis MethodsSeveral methods can be used for peritoneal dialysis, including Acute Intermittent Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis, and Automated Peritoneal Dialysis, also known as Continuous Cyclic Peritoneal Dialysis.Acute Intermittent Peritoneal Dialysis (AIPD) is used for patients with uremic...
Burn Injuries01:22

Burn Injuries

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Rat Burn Model to Study Full-Thickness Cutaneous Thermal Burn and Infection
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Peri-Operative Bacteraemia in Burn Patients. What Does it Mean?

G E Ramos1, M Resta, R Durlach

  • 1CEPAQ (Burns Unit), Benaim Foundation.

Annals of Burns and Fire Disasters
|October 13, 2011
PubMed
Summary

Bacteraemia, or bacteria in the blood, is common during burn wound care, particularly after surgery. However, these infections appear transient and lack clinical significance, questioning the need for antibiotic treatment.

Keywords:
bacteraemiaburnmeanpatientsperi-operativewhat

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Area of Science:

  • Medical Microbiology
  • Burn Surgery
  • Infectious Diseases

Background:

  • Bacteraemia frequently occurs during burn wound manipulation, especially after surgical excision.
  • The clinical significance and necessity of treating these bacteraemias remain controversial due to their apparent lack of consequences.

Purpose of the Study:

  • To prospectively investigate the incidence and characteristics of bacteraemia during surgical debridement in burn patients.
  • To determine the clinical relevance, timing, and risk factors associated with bacteraemia in this patient population.

Main Methods:

  • Prospective study of 35 surgical debridement procedures in 18 burn patients over 20 months.
  • Blood cultures collected before, during, and after surgical excision.
  • Analysis of bacteraemia rates, sources, timing, and correlation with patient factors like Total Body Surface Area (TBSA) burned.

Main Results:

  • Bacteraemia was detected in 28% of patients (10/35) and 15% of blood samples (16/105).
  • Two patterns observed: 'primary bacteraemia' (all three samples positive) and 'transient bacteraemia'.
  • Patients with >40% TBSA had a 4.3 times higher risk; observed physiological changes lacked clinical relevance.

Conclusions:

  • High rates of transient bacteraemia occur during burn wound manipulation, with no apparent clinical impact.
  • Bacteraemia induced by wound manipulation appeared after post-burn day 5.
  • Findings suggest current treatment protocols for bacteraemia in burn patients may warrant re-evaluation.