Related Experiment Video
Updated: May 28, 2026
12:33
High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities
Published on: November 15, 2013
[Not Available]
A Chaibdraa1, M S Medjellekh, A Saouli
1Centre de Réanimation et de Traitement des Brûlés, Annaba, Algérie.
Annals of Burns and Fire Disasters
|October 13, 2011
Summary
Pseudomonas aeruginosa is a major cause of severe hospital-acquired infections in burn centers. Limited antibiotic options highlight the need for strict prescription and prevention measures.
Area of Science:
- Medical Microbiology
- Infectious Diseases
- Hospital Epidemiology
Context:
- Pseudomonas is a significant opportunistic pathogen in burn units.
- Its virulence poses a major challenge in managing nosocomial infections.
- Understanding local bacterial ecology and antibiotic susceptibility is crucial.
Purpose:
- To evaluate the prevalence of Pseudomonas in the local bacterial ecology of a burn center.
- To assess the antibiotic susceptibility patterns of isolated Pseudomonas strains.
- To inform clinical practice and infection control strategies.
Summary:
- A retrospective study (June 2003-December 2005) analyzed 633 isolates from burn center patients, identifying 128 Pseudomonas (20.2%), predominantly Pseudomonas aeruginosa.
- Pseudomonas became the leading cause of infection after one week of hospitalization and was prevalent in ventilator-associated pneumonia.
- Antibiotic susceptibility testing revealed limited options, with only four molecules (ciprofloxacin, pefloxacin, piperacillin, ceftazidime) showing activity, and 2.4% resistance.
Impact:
- Findings underscore the severe prognosis of Pseudomonas nosocomial infections due to limited therapeutic choices.
- Highlights the critical need for adherence to antibiotic prescription guidelines.
- Emphasizes the importance of implementing robust infection prevention and control measures in burn units.
