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Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4
Published on: August 21, 2017
'Noteomielite' accompanied by acute amaurosis (1844). An early case of neuromyelitis optica
1Division of Molecular Neuroimmunology, Department of Neurology, University of Heidelberg, Germany. sven.jarius@med.uni-heidelberg.de
Abstract:
So far, only very little is known about the early history of neuromyelitis optica (Devic's syndrome). Here, we discuss a then widely recognized but now forgotten 1844 report by the Genoese physician Giovanni Battista Pescetto (1806-1884) on a 42-year-old man, who simultaneously developed acute amaurosis and cervical myelitis. Pescetto's report represents the earliest account of a case of neuromyelitis optica in the Western literature known so far.
