Related Experiment Video
Updated: May 28, 2026

Stem Cell-Derived Viral Ag-Specific T Lymphocytes Suppress HBV Replication in Mice
Published on: September 25, 2019
Adaptive immunity to hepatitis C virus
Mirjam B Zeisel1, Samira Fafi-Kremer, Eric Robinet
1Inserm, U748, 3 rue Koeberlé, F-67000 Strasbourg, France; E-Mails: mirjam.zeisel@unistra.fr (M.B.Z.); samira.fafi-kremer@chru-strasbourg.fr (S.F.-K.); e.robinet@unistra.fr (E.R.); francois.habersetzer@chru-strasbourg.fr (F.H.); thomas.baumert@unistra.fr (T.F.B.).
Abstract:
The precise role of adaptive immune responses in the clinical outcome of HCV infection is still only partially defined. Recent studies suggest that viral-host cell interactions during the acute phase of infection are essential for viral clearance or progression into chronic HCV infection. This review focuses on different aspects of the adaptive immune responses as determinants of the different outcomes of HCV infection, clearance or persistent infection, and outlines current concepts of HCV evasion strategies. Unravelling these important mechanisms of virus-host interaction will contribute to the development of novel strategies to prevent and control HCV infection.
Related Concept Videos
Hepatitis
Immune Response Against Viral Pathogens
NK Cells
NK cells are a crucial part of our innate immune system, acting as the first line of defense against viral infections. These cells can recognize and kill infected cells without prior exposure to the virus, effectively slowing down the spread of infection. Additionally, NK cells produce proinflammatory...
Viral Hepatitis I: Introduction
Cell-mediated Immune Responses
Retrovirus Life Cycles
Inhibitors of Viral Protein Synthesis

