Bunyaviruses and the type I interferon system
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Updated: May 28, 2026

High-throughput Quantitative Real-time RT-PCR Assay for Determining Expression Profiles of Types I and III Interferon Subtypes
Published on: March 24, 2015
Richard M Elliott1, Friedemann Weber
1Centre for Biomolecular Sciences, School of Biology, University of St. Andrews, St. Andrews, KY16 9ST, Scotland, UK;
Abstract:
The family Bunyaviridae contains more than 350 viruses that are distributed throughout the world. Most members of the family are transmitted by arthopods, and several cause disease in man, domesticated animals and crop plants. Despite being recognized as an emerging threat, details of the virulence mechanisms employed by bunyaviruses are scant. In this article we summarise the information currently available on how these viruses are able to establish infection when confronted with a powerful antiviral interferon system.
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