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Updated: May 28, 2026

Purification of Viral DNA for the Identification of Associated Viral and Cellular Proteins

Purification of Viral DNA for the Identification of Associated Viral and Cellular Proteins

Published on: August 31, 2017

Actin in herpesvirus infection.

Kari L Roberts¹, Joel D Baines

¹Department of Microbiology and Immunology, Cornell University, Ithaca, NY 14853, USA. klr54@cornell.edu

|October 14, 2011

Summary

Herpesviruses utilize the cell

Area of Science:

Cell Biology
Virology
Molecular Biology

Background:

Actin dynamics are crucial for fundamental cellular functions.
Herpesviruses are known to interact with host cell machinery.

Purpose of the Study:

To review the role of actin and myosin motors in herpesvirus life cycle.
To identify potential therapeutic targets within these interactions.

Main Methods:

Literature review of existing studies.
Analysis of molecular mechanisms involved.

Main Results:

Herpesviruses hijack actin cytoskeleton for entry.
Viral capsids are transported intracellularly using actin-myosin.
Actin is involved in herpesvirus egress.

Keywords:

Rho GTPase actin herpes myosin

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Conclusions:

Actin and myosin motors are essential for multiple stages of herpesvirus infection.
Targeting these host-pathogen interactions may offer novel antiviral strategies.