Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: May 28, 2026

Translational Orthotopic Models of Glioblastoma Multiforme

Translational Orthotopic Models of Glioblastoma Multiforme

Published on: February 17, 2023

Graph based spatial position mapping of low-grade gliomas.

Sarah Parisot¹, Hugues Duffau, Stéphane Chemouny

¹Laboratoire MAS, Ecole Centrale Paris, Chatenay Malabry, France.

Medical Image Computing and Computer-Assisted Intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention

|October 15, 2011

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The future of neurosurgical oncology lies in cognitive neurosciences: understanding brain processing is much more valuable than surgical technology.

Frontiers in oncology·2026

Same author

What is the actual role of intraoperative MRI on long-term onco-functional outcome of surgery for low-grade glioma? A systematic review.

Journal of neuro-oncology·2026

Same author

Intractable epilepsy before and/or after awake functional mapping-based surgery for IDH-mutant grade 2 glioma: a consecutive series of 105 patients.

Journal of neurosurgery·2026

Same author

Individualized multiparadigm mapping and standardized tablet-based task administration during awake craniotomy: associations with return to work and survival in diffuse gliomas.

Journal of neurosurgery·2026

Same author

EDNRB-dependent endothelin signaling reduces proliferation and promotes proneural-to-mesenchymal transition in gliomas.

Molecular oncology·2026

Same author

Tracking evolving cortical plasticity in recurrent low-grade glioma patients: a prospective pilot study based on serial intraoperative awake direct electrostimulation and transcranial magnetic stimulation mappings.

Journal of neurosurgery·2026

This study introduces a novel graphical model for precise spatial classification of low-grade gliomas (WHO grade II) brain tumors. The approach improves upon traditional methods, offering better statistical interpretation of tumor appearance and distribution.

Area of Science:

Neuro-oncology
Computational Biology
Medical Imaging Analysis

Background:

Low-grade gliomas (WHO grade II) are infiltrative brain tumors.
Current spatial classification by cerebral lobes lacks accuracy and statistical interpretation.
Understanding tumor spatial distribution is crucial for diagnosis and treatment.

Purpose of the Study:

To develop a novel graphical model for inferring the spatial position of low-grade gliomas.
To improve the accuracy and statistical interpretability of glioma spatial classification.
To provide a new method for analyzing tumor distribution patterns.

Main Methods:

Formulated the problem as a graph topology optimization.
Represented tumors as graph nodes and dependencies as connections.

More Related Videos

Co-culture of Glioblastoma Stem-like Cells on Patterned Neurons to Study Migration and Cellular Interactions

Co-culture of Glioblastoma Stem-like Cells on Patterned Neurons to Study Migration and Cellular Interactions

Published on: February 24, 2021

Related Experiment Videos

Last Updated: May 28, 2026

Translational Orthotopic Models of Glioblastoma Multiforme

Translational Orthotopic Models of Glioblastoma Multiforme

Published on: February 17, 2023

Co-culture of Glioblastoma Stem-like Cells on Patterned Neurons to Study Migration and Cellular Interactions

Co-culture of Glioblastoma Stem-like Cells on Patterned Neurons to Study Migration and Cellular Interactions

Published on: February 24, 2021

Utilized unsupervised clustering for spatial position mapping.

Main Results:

The proposed graphical model demonstrated promising results.
Leave-one-out cross-validation outperformed conventional dimensionality reduction methods.
The model's findings align with physiological studies on tumor spatial distributions.

Conclusions:

The novel graphical model offers a more accurate approach to spatial classification of low-grade gliomas.
This method provides better statistical insights into tumor appearance and distribution.
The approach has the potential to enhance understanding of glioma behavior and interactions.