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Related Concept Videos

In Vitro Fertilization01:24

In Vitro Fertilization

In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
In vitro Mutagenesis01:16

In vitro Mutagenesis

To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.
In-vitro Mutagenesis01:16

In-vitro Mutagenesis

To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.

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Updated: May 28, 2026

OP-IVM: Combining In vitro Maturation after Oocyte Retrieval with Gynecological Surgery
05:31

OP-IVM: Combining In vitro Maturation after Oocyte Retrieval with Gynecological Surgery

Published on: May 9, 2021

In vitro maturation: a five-year experience.

Sabine Roesner1, Michael VON Wolff2, Ingeborg Eberhardt1

  • 1Department of Gynecological Endocrinology and Fertility Disorders, Ruprecht-Karls University of Heidelberg, Heidelberg, Germany.

Acta Obstetricia Et Gynecologica Scandinavica
|October 15, 2011
PubMed
Summary
This summary is machine-generated.

In vitro maturation (IVM) offers a convenient, low-cost assisted reproduction option using reduced follicle-stimulating hormone (FSH) dosages. While pregnancy rates were modest, IVM provides a valuable alternative for specific patient groups.

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Human Egg Maturity Assessment and Its Clinical Application
08:51

Human Egg Maturity Assessment and Its Clinical Application

Published on: August 19, 2019

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Last Updated: May 28, 2026

OP-IVM: Combining In vitro Maturation after Oocyte Retrieval with Gynecological Surgery
05:31

OP-IVM: Combining In vitro Maturation after Oocyte Retrieval with Gynecological Surgery

Published on: May 9, 2021

Human Egg Maturity Assessment and Its Clinical Application
08:51

Human Egg Maturity Assessment and Its Clinical Application

Published on: August 19, 2019

Area of Science:

  • Reproductive Medicine
  • Assisted Reproductive Technology (ART)
  • In Vitro Maturation (IVM)

Background:

  • In vitro maturation (IVM) is an underutilized assisted reproduction technique.
  • IVM may benefit patients requiring reduced follicle-stimulating hormone (FSH) application.
  • This study reviews a five-year experience with IVM.

Purpose of the Study:

  • To evaluate the outcomes of in vitro maturation (IVM) in a clinical setting.
  • To assess pregnancy rates and live birth rates following IVM procedures.
  • To identify patient populations benefiting from IVM, such as those with Polycystic Ovary Syndrome (PCOS) or a history of Ovarian Hyperstimulation Syndrome (OHSS).

Main Methods:

  • Retrospective observational study of 115 patients undergoing IVM from February 2005 to December 2009.
  • Patients included those with PCOS and OHSS.
  • Standardized IVM protocol involving low-dose FSH stimulation, oocyte retrieval, in vitro culture, fertilization, and embryo transfer.

Main Results:

  • A total of 215 oocyte retrievals and 177 embryo transfers were performed.
  • The primary indications for IVM were PCOS (71.7%) and OHSS (15.0%).
  • The pregnancy rate per transfer was 15.3%, resulting in 7.3% live births; cryotransfers yielded three additional pregnancies.

Conclusions:

  • Despite lower pregnancy rates compared to conventional IVF, IVM is a convenient and cost-effective option.
  • IVM's advantages include reduced FSH dosages and fewer patient appointments.
  • IVM serves as a valuable alternative ART method for selected patient groups.