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Updated: May 28, 2026
10:51
Microscale Vortex-assisted Electroporator for Sequential Molecular Delivery
Published on: August 7, 2014
Drug delivery by electropulsation: Recent developments in oncology
J Teissié1, J M Escoffre, A Paganin
1CNRS, IPBS (Institut de Pharmacologie et de Biologie Structurale), 205 route de Narbonne, F-31077 Toulouse, France. justin.teissie@ipbs.fr
International Journal of Pharmaceutics
|October 15, 2011
Summary
Electro-permeabilisation temporarily modifies cell membranes, enabling polar compounds to enter cells. This technique is currently used to treat skin tumors and shows promise for future cancer therapies.
Area of Science:
- Biomedical Engineering
- Cell Biology
- Oncology
Background:
- Electro-permeabilisation is a method to reversibly alter cell membranes.
- This technique facilitates the entry of polar molecules into the cytoplasm.
- It is currently employed in clinical settings for treating solid tumors.
Purpose of the Study:
- To summarize the current applications and future potential of electro-permeabilisation in cancer treatment.
Main Methods:
- Review of existing clinical applications of electro-permeabilisation.
- Analysis of emerging research and predicted future uses.
Main Results:
- Electro-permeabilisation is effective for eradicating cutaneous solid tumors.
- The technology is being explored for broader anti-cancer applications.
Conclusions:
- Electro-permeabilisation is a validated clinical tool for specific cancers.
- Further research is expected to expand its therapeutic scope in oncology.
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