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Related Concept Videos

Computed Tomography01:10

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
Positron Emission Tomography01:29

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
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Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...

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Related Experiment Video

Updated: May 28, 2026

Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography
08:50

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Published on: February 9, 2019

Structured three-dimensional optical phantom for optical coherence tomography.

Andrea Curatolo1, Brendan F Kennedy, David D Sampson

  • 1Optical+Biomedical Engineering Laboratory, School of Electrical, Electronic and Computer Engineering, The University of Western Australia, 35 Stirling Highway, Crawley, Western Australia 6009, Australia. andrea.curatolo@uwa.edu.au

Optics Express
|October 15, 2011
PubMed
Summary
This summary is machine-generated.

We developed a 3D tissue phantom for optical coherence tomography (OCT) using a novel fabrication method. This phantom aids in assessing OCT performance and developing imaging standards.

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Area of Science:

  • Biomedical Optics
  • Medical Imaging Technology

Background:

  • Optical coherence tomography (OCT) is a valuable imaging modality.
  • Standardized phantoms are needed for OCT performance assessment.

Purpose of the Study:

  • To create a 3D structured tissue-mimicking phantom for OCT.
  • To demonstrate its utility in evaluating OCT performance and developing standards.

Main Methods:

  • Fabrication of a silicone-based phantom with titanium dioxide additive.
  • Utilized lithographic casting for precise geometry control.
  • Characterization and OCT imaging of fabricated phantoms.

Main Results:

  • Successfully fabricated well-defined 3D geometries with relevant optical contrast.
  • Demonstrated phantom utility in assessing a spatial-diversity speckle reduction technique.
  • Phantoms showed mesoscopic feature sizes suitable for OCT.

Conclusions:

  • The developed phantom is a valuable tool for OCT development.
  • Enables quantitative performance assessment and standardization of OCT imaging.
  • Facilitates advancements in OCT technology and applications.