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Related Experiment Video

Updated: May 28, 2026

Fluorescence detection methods for microfluidic droplet platforms
14:16

Fluorescence detection methods for microfluidic droplet platforms

Published on: December 10, 2011

Versatile optofluidic ring resonator lasers based on microdroplets.

Wonsuk Lee1, Yunhan Luo, Qiran Zhu

  • 1Department of Biomedical Engineering, University of Michigan, 1101 Beal Ave., Ann Arbor, MI 48109, USA.

Optics Express
|October 15, 2011
PubMed
Summary
This summary is machine-generated.

We created a new microdroplet laser using an optofluidic ring resonator. This novel laser achieves a significantly lower lasing threshold and tunable wavelengths for advanced sensing applications.

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Area of Science:

  • Optofluidics
  • Laser Technology
  • Microfluidics

Background:

  • Optofluidic ring resonators (OFRRs) offer potential for miniaturized lasers.
  • Previous microdroplet laser systems faced challenges with high lasing thresholds and limited tunability.

Purpose of the Study:

  • To develop a novel nanoliter-sized microdroplet laser.
  • To improve lasing efficiency and enable wavelength tunability.
  • To demonstrate the platform's utility for sensing applications.

Main Methods:

  • Generation of nL-sized microdroplets using immiscible fluids in a microfluidic channel.
  • Integration of microdroplets into a capillary optofluidic ring resonator (OFRR).
  • Wavelength tuning via fluorescence resonance energy transfer (FRET) by merging dye-doped droplets.

Main Results:

  • Achieved lasing emission from low refractive index (RI) droplets within a high RI carrier fluid.
  • Obtained a low lasing threshold of 1.54 µJ/mm², over six times lower than state-of-the-art.
  • Demonstrated convenient coupling of lasing emission into an optical fiber.
  • Successfully tuned lasing wavelength through FRET in merged droplets.

Conclusions:

  • The developed OFRR microdroplet laser offers superior lasing characteristics and wavelength tunability.
  • The platform is versatile for high-performance optofluidic lasers.
  • It presents a promising tool for bio/chemical sensing with minimal sample volumes.