Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 28, 2026

Stretching Short Sequences of DNA with Constant Force Axial Optical Tweezers
08:48

Stretching Short Sequences of DNA with Constant Force Axial Optical Tweezers

Published on: October 13, 2011

Multiplying optical tweezers force using a micro-lever.

Chih-Lang Lin1, Yi-Hsiung Lee, Chin-Te Lin

  • 1Inst. of Biomedical Engineering and Material, Central Taiwan Univ. of Science and Technology, Taichung, Taiwan. cllin101943@ctust.edu.tw

Optics Express
|October 15, 2011
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Combined Therapeutic Effect of Lenvatinib and ADI-PEG 20 in Advanced Hepatocellular Carcinoma: A Case Report.

In vivo (Athens, Greece)·2026
Same author

Reply to correspondence: Sodium-Glucose Cotransporter-2 Inhibitors and Liver Outcomes in Metabolic Dysfunction-associated Steatotic Liver Disease.

Clinical and molecular hepatology·2026
Same author

Challenges and Innovations in MASLD and T2DM: Strengthening Personalized Medicine with SGLT2 Inhibitors.

Clinical and molecular hepatology·2026
Same author

Outcomes of robotic liver resection and intraoperative radiofrequency ablation for hepatocellular carcinoma in posterior segments VII and VIII.

World journal of gastrointestinal surgery·2026
Same author

Machine learning survival prediction in esophageal cancer using radiomics and body composition from pretreatment and follow-up T12-level computed tomography.

World journal of gastrointestinal oncology·2026
Same author

Advancing free-breathing liver diffusion-weighted imaging with Propeller-EPI: Improved image quality and ADC repeatability.

Medical physics·2025
Same journal

Denoising algorithm of Φ-OTDR systems based on adaptive fractional wavelet transform denoising.

Optics express·2026
Same journal

Millisecond photon-to-photon latency and high-speed volumetric projection system for optogenetics.

Optics express·2026
Same journal

Polarization-encoded coaxial structured light for high-precision 3D surface profilometry.

Optics express·2026
Same journal

Discrete freeform optical design based on collaborative optimization of point cloud and local normals.

Optics express·2026
Same journal

Ultrafast ghost imaging with 25 GHz speckle switching and wavelength-division multiplexing.

Optics express·2026
Same journal

Atomic vapor cells fabricated by femtosecond laser welding of standard-optical-quality glass.

Optics express·2026
See all related articles

Researchers developed a photo-driven micro-lever using 3D microfabrication to amplify optical forces. This device precisely manipulates micro-scale objects with optical tweezers, multiplying applied force by nine.

Area of Science:

  • Micro-optics
  • Nanotechnology
  • Mechanical Engineering

Background:

  • Optical forces are crucial for manipulating micro-scale objects.
  • Existing methods for optical force manipulation require further enhancement in precision and amplification.
  • 3D microfabrication offers novel pathways for creating advanced micro-mechanical devices.

Purpose of the Study:

  • To design and fabricate a photo-driven micro-lever capable of multiplying optical forces.
  • To enable precise manipulation of micro-scale components using optical tweezers.
  • To investigate the relationship between applied optical force and spring characteristics through leverage principles.

Main Methods:

  • Utilizing two-photon polymerization for 3D microfabrication of the micro-lever.

More Related Videos

Direct Force Measurements of Subcellular Mechanics in Confinement using Optical Tweezers
09:56

Direct Force Measurements of Subcellular Mechanics in Confinement using Optical Tweezers

Published on: August 31, 2021

Measurement of Tension Release During Laser Induced Axon Lesion to Evaluate Axonal Adhesion to the Substrate at Piconewton and Millisecond Resolution
09:31

Measurement of Tension Release During Laser Induced Axon Lesion to Evaluate Axonal Adhesion to the Substrate at Piconewton and Millisecond Resolution

Published on: May 27, 2013

Related Experiment Videos

Last Updated: May 28, 2026

Stretching Short Sequences of DNA with Constant Force Axial Optical Tweezers
08:48

Stretching Short Sequences of DNA with Constant Force Axial Optical Tweezers

Published on: October 13, 2011

Direct Force Measurements of Subcellular Mechanics in Confinement using Optical Tweezers
09:56

Direct Force Measurements of Subcellular Mechanics in Confinement using Optical Tweezers

Published on: August 31, 2021

Measurement of Tension Release During Laser Induced Axon Lesion to Evaluate Axonal Adhesion to the Substrate at Piconewton and Millisecond Resolution
09:31

Measurement of Tension Release During Laser Induced Axon Lesion to Evaluate Axonal Adhesion to the Substrate at Piconewton and Millisecond Resolution

Published on: May 27, 2013

  • Integrating an optical trapping sphere, beam, and pivot to form a second-class lever.
  • Employing optical tweezers for precise manipulation and force application on the micro-lever.
  • Incorporating a micro-spring to measure induced forces and characterize spring properties.
  • Main Results:

    • Successful demonstration of optical tweezers driving the micro-lever at the micron scale.
    • Achieved multiplication of applied optical force by a factor of 9 through the lever's arm ratio.
    • Measured optical forces ranging from 100 to 300 pN with laser powers of 100 to 300 mW.
    • Experimental results showed good agreement with simulations of the micro-spring's properties.

    Conclusions:

    • The photo-driven micro-lever effectively multiplies optical forces, enhancing manipulation capabilities.
    • The developed 3D-microfabricated device offers precise control and force amplification for micro-scale applications.
    • This study validates the principle of leverage for optical force manipulation and provides a foundation for further advancements in micro-mechanics.