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Updated: May 28, 2026

A Novel Method: Super-selective Adrenal Venous Sampling
Published on: September 15, 2017
Conventional imaging in adrenocortical carcinoma: update and perspectives
1Division of Endocrinology, Diabetes, Metabolism, Nutrition, and Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA. young.william@mayo.edu
Computed tomography (CT) and magnetic resonance imaging (MRI) have revolutionized adrenocortical carcinoma imaging over 100 years. These advanced techniques are crucial for diagnosing adrenal tumors, assessing spread, and guiding treatment decisions.
Area of Science:
- Radiology and Medical Imaging
- Oncology
- Endocrinology
Background:
- Adrenocortical carcinoma imaging has evolved significantly over the past century.
- Early diagnostic methods relied heavily on clinical observation and limited imaging.
- Technological advancements have transformed the assessment of adrenal malignancies.
Purpose of the Study:
- To review the historical evolution of conventional imaging for adrenocortical carcinoma.
- To highlight the current diagnostic and management roles of CT and MRI.
- To project future trends in adrenal cancer imaging.
Main Methods:
- Historical case review from Mayo Clinic archives.
- Comprehensive literature review on adrenocortical carcinoma imaging.
- Analysis of the development and application of CT and MRI.
Main Results:
- Imaging options were limited in the early 20th century, relying on clinical acumen.
- Computed tomography (CT) and magnetic resonance imaging (MRI) offer remarkable advancements.
- CT and MRI accurately determine malignancy, assess local invasion, and detect metastases.
Conclusions:
- CT and MRI are indispensable tools for guiding medical and surgical management of adrenocortical carcinoma.
- Current advanced imaging techniques will likely be superseded by future technologies.
- The study underscores the critical role of imaging in modern cancer care.
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