Facile synthesis of monodisperse superparamagnetic Fe3O4 Core@hybrid@Au shell nanocomposite for bimodal imaging and photothermal therapy
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Published on: February 20, 2016
Wenjie Dong1, Yongsheng Li, Dechao Niu
1Key Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai, China.
Abstract:
A simple seed-mediated growth route is developed to fabricate monodisperse, uniform superparamagnetic Fe(3)O(4) core/gold shell structured nanocomposites with tunable sizes and optical properties, in which gold seed formation and attachment onto the core surface via S-Au covalent bonding proceeds almost simultaneously in the one-pot synthesis. The as-prepared nanocomposite is demonstrated to have a great potential for magnetic resonance imaging (MRI)-guided, focused photothermal tumor therapy under near-IR laser radiation.
