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Related Experiment Video

Updated: May 28, 2026

Development of an IFN-γ ELISpot Assay to Assess Varicella-Zoster Virus-specific Cell-mediated Immunity Following Umbilical Cord Blood Transplantation

Development of an IFN-γ ELISpot Assay to Assess Varicella-Zoster Virus-specific Cell-mediated Immunity Following Umbilical Cord Blood Transplantation

Published on: July 9, 2014

Herpes zoster during pregnancy.

Anna Pupco¹, Pina Bozzo, Gideon Koren

¹Hospital for Sick Children, Toronto, ON, Canada.

Canadian Family Physician Medecin De Famille Canadien

|October 15, 2011

Summary

This summary is machine-generated.

Herpes zoster (HZ) during pregnancy does not increase fetal risk. However, pregnant women not immune to varicella-zoster virus exposed to HZ may develop chickenpox.

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Area of Science:

Obstetrics and Gynecology
Infectious Diseases
Viral Pathogenesis

Background:

Varicella-zoster virus (VZV) causes both chickenpox and herpes zoster (shingles).
Chickenpox in pregnancy is associated with teratogenic risks to the fetus.
The potential teratogenicity of herpes zoster in pregnancy requires clarification.

Observation:

A pregnant patient presented with herpes zoster affecting the T11 to T12 dermatomes.
The patient was 32 years old, gravida 2, para 1.

Findings:

Herpes zoster infection during pregnancy is not linked to an increased risk of fetal harm.
Nonimmune pregnant individuals exposed to herpes zoster may contract chickenpox.

Implications:

This finding reassures clinicians regarding herpes zoster cases in pregnant patients.
Highlights the importance of varicella-zoster virus immunity status in pregnant women exposed to shingles.
Distinguishes the fetal risks associated with primary VZV infection versus VZV reactivation.