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Updated: May 28, 2026

Diagnosing Pulmonary Tuberculosis with the Xpert MTB/RIF Test
Published on: April 9, 2012
Xpert MTB/RIF assay for diagnosis of pleural tuberculosis
Sven O Friedrich1, Florian von Groote-Bidlingmaier, Andreas H Diacon
1Department of Biomedical Sciences, Faculty of Health Sciences, P.O. Box 19063, Tygerberg 7505, South Africa.
Abstract:
We prospectively investigated the diagnostic utility of the Xpert MTB/RIF (Mycobacterium tuberculosis/rifampin [RIF] resistance) assay in 20 cases with confirmed tuberculous pleural effusion. The sensitivity and specificity of the Xpert assay in pleural fluid were 25% and 100%, respectively. All cases positive by the Xpert assay were also positive by pleural fluid culture.
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