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Detection of an unusual van genotype in a vancomycin-resistant Enterococcus faecium hospital isolate
Jeanette W P Teo1, Prabha Krishnan, Roland Jureen
1Department of Laboratory Medicine, National University Hospital, Singapore 119074, Republic of Singapore. jeanette_teo@nuhs.edu.sg
Abstract:
We highlight the detection of a rare vanM genotype in Enterococcus faecium. This isolate exhibited a VanB phenotype, with high levels of resistance to vancomycin (MIC, >256 mg/liter) and susceptibility to teicoplanin (MIC, 1 mg/liter). It was, however, vanB negative by PCR. Further screening for other van loci revealed the presence of a complete vanM operon.
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