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Related Concept Videos

Clinical Trials: Overview01:11

Clinical Trials: Overview

Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
Companionate Love01:27

Companionate Love

Companionate love is a fundamental aspect of long-term relationships, characterized by deep affection, mutual respect, and emotional intimacy. Unlike passionate love, which is driven by intense emotions and physical attraction but often declines over time, companionate love remains stable and can even strengthen with shared experiences and commitment. Psychological and biological mechanisms underpin this enduring form of love, influencing relationship longevity and satisfaction.Stability and...
Couples Therapy01:26

Couples Therapy

Couples therapy is a therapeutic approach designed to help individuals in intimate relationships address conflicts, improve communication, and foster healthier dynamics. It is appropriate for couples at various stages, including those who are dating, married, or in long-term partnerships, and aims to support partners in navigating their unique relational challenges.
Core Principles and Techniques
Couples therapy often incorporates cognitive-behavioral principles to identify and modify negative...
Clinical Trials01:16

Clinical Trials

Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
Social Exchange Theory02:06

Social Exchange Theory

We have discussed why we form relationships, what attracts us to others, and different types of love. But what determines whether we are satisfied with and stay in a relationship? One theory that provides an explanation is social exchange theory. According to social exchange theory, we act as naïve economists in keeping a tally of the ratio of costs and benefits of forming and maintaining a relationship with others (Rusbult & Van Lange, 2003).
Reliability and Validity01:29

Reliability and Validity

Reliability and validity are two important considerations that must be made with any type of data collection. Reliability refers to the ability to consistently produce a given result. In the context of psychological research, this would mean that any instruments or tools used to collect data do so in consistent, reproducible ways.

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Updated: May 28, 2026

How to Find Effects of Stimulus Processing on Event Related Brain Potentials of Close Others when Hyperscanning Partners
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Published on: May 31, 2018

The PARTNER trial after 1 year.

Jennifer Taylor

    European Heart Journal
    |October 15, 2011
    PubMed
    Summary
    This summary is machine-generated.

    The PARTNER trial found similar 1-year survival rates for transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement (SAVR) in high-risk patients. However, the two procedures had different complication profiles.

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    Area of Science:

    • Cardiovascular Medicine
    • Interventional Cardiology
    • Cardiac Surgery

    Background:

    • Aortic valve stenosis is a significant cause of morbidity and mortality.
    • Transcatheter aortic valve replacement (TAVR) has emerged as an alternative to surgical aortic valve replacement (SAVR) for high-risk patients.
    • The PARTNER trial provides critical data comparing these approaches.

    Purpose of the Study:

    • To compare the 1-year mortality and complication rates between TAVR and SAVR in high-risk patients with aortic stenosis.
    • To inform clinical decision-making for severe aortic stenosis treatment.

    Main Methods:

    • The study involved high-risk patients undergoing either TAVR or SAVR.
    • Mortality and complication data were collected and analyzed at the 1-year follow-up point.
    • Statistical analysis was performed to compare outcomes between the two treatment groups.

    Main Results:

    • One-year mortality was equivalent between the TAVR and SAVR groups.
    • Significant differences were observed in the types and rates of complications between the two procedures.
    • Specific complication profiles require detailed examination for each treatment modality.

    Conclusions:

    • TAVR and SAVR demonstrate comparable 1-year survival for high-risk patients.
    • The choice between TAVR and SAVR should consider the distinct complication risks associated with each procedure.
    • Further analysis of complication data is warranted to guide patient selection.