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Related Experiment Video

Updated: May 28, 2026

Demonstrating a Multi-drug Resistant Mycobacterium tuberculosis Amplification Microarray

Demonstrating a Multi-drug Resistant Mycobacterium tuberculosis Amplification Microarray

Published on: April 25, 2014

Molecular diagnosis using multi drug delivery network and stability.

M A Jalil¹, K Innate, N Suwanpayak

¹Institute of Advanced Photonics Science, Nanotechnology Research Alliance, Universiti Teknologi Malaysia, Johor Bahru, Malaysia.

Artificial Cells, Blood Substitutes, and Immobilization Biotechnology

|October 18, 2011

Summary

Intense optical vortices trap and move molecules for dynamic drug delivery and diagnostics within tiny molecular bus networks. This enables potential applications in human embedded devices for precise medical interventions.

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Last Updated: May 28, 2026

Demonstrating a Multi-drug Resistant Mycobacterium tuberculosis Amplification Microarray

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Published on: April 25, 2014

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry

Published on: April 23, 2019

Area of Science:

Optics and Photonics
Nanotechnology
Biomedical Engineering

Background:

Existing drug delivery and diagnostic systems face limitations in miniaturization and precision.
Molecular manipulation at the nanoscale is crucial for advanced therapeutic and diagnostic applications.

Purpose of the Study:

To develop a novel method for dynamic trapping and transport of molecules using optical vortices.
To demonstrate the feasibility of integrating this molecular manipulation technique into miniaturized diagnostic devices.

Main Methods:

Generating intense optical vortices using a pair of tweezers within the PANDA ring resonator.
Utilizing molecular bus networks for controlled movement and targeting of trapped molecules (drug volumes).

Main Results:

Successful dynamic trapping and controlled movement of molecules within the molecular bus networks.
Demonstrated potential for performing diagnosis or drug delivery within the network.
Achieved controllable channel spacing for trapped molecules.

Conclusions:

The proposed optical vortex system offers a novel approach for precise molecular manipulation.
The technology enables miniaturized diagnostic and drug delivery systems suitable for embedded devices.
This method provides a foundation for advanced nanoscale therapeutic and diagnostic platforms.