Sirtuins: multifaceted drug targets.

S P Chakrabarty1, H Balaram, S Chandrasekaran

  • 1Aurigene Discovery Technologies Ltd, Electronic City, Bangalore 560100, India.

Summary

Sirtuin proteins (Sir2) regulate key cellular processes like aging and cancer. Researchers use genetics and medicinal chemistry to discover Sir2 modulators for pharmacological and chemical genetic studies.

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