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Anti-inflammatory activity of Abutilon indicum extract
Priyanka Tripathi1, N S Chauhan, J R Patel
1Shri Ramnathsingh Mahavidyalaya-Pharmacy, Gormi, Bhind 477660, Madhya Pradesh, India.
Natural Product Research
|October 18, 2011
Summary
The ethanolic extract of Abutilon indicum demonstrated significant anti-inflammatory effects in rats, supporting its traditional medicinal use. This natural compound
Area of Science:
- Pharmacology and Traditional Medicine
- Phytochemistry and Natural Products Research
Background:
- Abutilon indicum Linn. is widely recognized in traditional medicine for various biological activities.
- Its anti-inflammatory properties are frequently cited, necessitating scientific validation.
Purpose of the Study:
- To evaluate the in vivo anti-inflammatory activity of the ethanolic extract of Abutilon indicum Linn.
- To scientifically validate the traditional use of Abutilon indicum for treating inflammation.
Main Methods:
- The study utilized the carrageenan-induced paw edema model in healthy Wistar albino rats.
- Different doses (250, 500, and 750 mg/kg) of the ethanolic extract were administered.
Main Results:
- The ethanolic extract of Abutilon indicum exhibited significant anti-inflammatory activity.
- The observed activity was dose-dependent, with higher doses showing greater efficacy.
- The extract's anti-inflammatory effect was comparable to the standard drug, ibuprofen.
Conclusions:
- The findings scientifically support the traditional application of Abutilon indicum in managing inflammatory conditions.
- The ethanolic extract possesses notable anti-inflammatory properties that warrant further investigation.
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