Related Experiment Video
Updated: May 28, 2026
09:36
Assessment of Child Anthropometry in a Large Epidemiologic Study
Published on: February 2, 2017
Association between atopic dermatitis and obesity in adulthood
J I Silverberg1, N B Silverberg, M Lee-Wong
1Department of Dermatology, St Luke's-Roosevelt Hospital and Beth Israel Medical Centers, New York, NY 10025, USA. jonathanisilverberg@gmail.com
The British Journal of Dermatology
|October 18, 2011
Summary
Adult obesity is linked to a higher risk of developing atopic dermatitis (AD). This study suggests weight management may be important for preventing or reducing AD severity in adults.
Area of Science:
- Dermatology
- Epidemiology
- Public Health
Background:
- Childhood obesity is a known risk factor for atopic dermatitis (AD) severity.
- The association between adult obesity and AD risk requires further investigation.
Purpose of the Study:
- To investigate the relationship between adult obesity and the risk of developing atopic dermatitis (AD).
Main Methods:
- A retrospective case-control study involving 2090 adults.
- Data collected via questionnaires, height/weight measurements, and skin-prick testing from 1994-2003.
Main Results:
- Adult obesity was significantly associated with an increased risk of atopic dermatitis (aOR 1.43, P=0.01).
- Obesity also correlated with increased atopic asthma risk (aOR 1.98, P<0.0001).
- The link between obesity and AD remained significant after controlling for other allergic conditions.
Conclusions:
- Adult obesity is a significant risk factor for atopic dermatitis (AD).
- Further research is recommended to explore the potential benefits of weight loss in managing AD.
Related Concept Videos
01:24Obesity
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in adipocytes...
01:02Hypodermis
The hypodermis (the subcutaneous layer or superficial fascia) is present directly below the dermis. It connects the skin to the underlying fascia (fibrous tissue) of the bones and muscles. It is not strictly a part of the skin, although the border between the hypodermis and dermis can be difficult to distinguish. The hypodermis consists of well-vascularized, loose, areolar connective tissue and adipose tissue, which functions as a mode of fat storage and provides insulation and cushioning for...
01:25Pharmacokinetics in Obese Patients: Drug Absorption and Distribution
Obesity significantly alters the pharmacokinetic processes of drug absorption and distribution, presenting unique challenges in medical treatment. The increased fat tissue and decreased lean muscle in obese individuals can significantly affect how drugs are absorbed into the body and distributed across different tissues. This alteration can lead to variances in the effectiveness and safety of medications, necessitating adjustments in dosing or drug selection for obese patients.One notable...
01:21Drug Dosing: Obese Patients
In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
01:26Type II Diabetes I: Introduction
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by insulin resistance, in which target tissues such as the liver, muscle, and adipose tissue respond poorly to insulin. It is also associated with inadequate compensatory insulin secretion, where pancreatic β-cells fail to produce sufficient insulin. Together, these abnormalities lead to persistent hyperglycemia.EtiologyT2DM develops through a complex interaction of genetic predisposition and environmental or...
01:20Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion
Drug metabolism, a critical process in the liver, involves two primary phases: Phase I reactions and Phase II conjugation. Obesity introduces significant alterations in this metabolic process, primarily due to fatty infiltration of the liver, leading to conditions such as nonalcoholic fatty liver disease (NAFLD). This condition can modify the activities of both Phase I and II enzymes, impacting how drugs are metabolized in obese patients.Phase I metabolism sees variable effects across...