Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Genomics

Genomics

Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...

Human Genetics

Human Genetics

Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...

Genome Size and the Evolution of New Genes

Genome Size and the Evolution of New Genes

While every living organism has a genome of some kind (be it RNA, or DNA), there is considerable variation in the sizes of these blueprints. One major factor that impacts genome size is whether the organism is prokaryotic or eukaryotic. In prokaryotes, the genome contains little to no non-coding sequence, such that genes are tightly clustered in groups or operons sequentially along the chromosome. Conversely, the genes in eukaryotes are punctuated by long stretches of non-coding sequence.

Genome Size and the Evolution of New Genes

Genome Size and the Evolution of New Genes

While every living organism has a genome of some kind (be it RNA, or DNA), there is considerable variation in the sizes of these blueprints. One major factor that impacts genome size is whether the organism is prokaryotic or eukaryotic. In prokaryotes, the genome contains little to no non-coding sequence, such that genes are tightly clustered in groups or operons sequentially along the chromosome. Conversely, the genes in eukaryotes are punctuated by long stretches of non-coding sequence.

Evolutionary Relationships through Genome Comparisons

Evolutionary Relationships through Genome Comparisons

Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Defining the threshold duration of candidemia associated with poor outcomes: Redefining persistent candidemia.

The Journal of infection·2026

Same author

Real-World Experience with Cefiderocol in Hematologic Patients with Malignancies.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases·2026

Same author

Time to positivity as a diagnostic tool for catheter-related candidemia: A species-specific analysis.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases·2026

Same author

The Combined Role of Cognitive, Plasma, Volumetric and EEG Markers Along the Alzheimer's Disease Continuum in Down Syndrome.

Journal of intellectual disability research : JIDR·2026

Same author

Pulmonary Mucosa-Associated Lymphoid Tissue Lymphoma and Tuberculosis: A Rare Association With Diagnostic and Therapeutic Challenges.

Journal of medical cases·2026

Same author

Effects of Siltuximab Versus Corticosteroids in Preventing COVID-19 Pneumonia Disease Progression: Multicentre, Open-Label, Randomized Clinical Trial.

Clinical and translational science·2026

Search research articles

Related Experiment Video

Updated: May 28, 2026

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.

Published on: May 6, 2010

The human genome: a multifractal analysis.

Pedro A Moreno¹, Patricia E Vélez, Ember Martínez

¹Escuela de Ingeniería de Sistemas y Computación, Universidad del Valle, Santiago de Cali, Colombia. pedro.moreno@correounivalle.edu.co

|October 18, 2011

Summary

This summary is machine-generated.

The human genome exhibits multifractality, a complex behavior strongly linked to Alu elements. This finding suggests a non-linear organization with implications for genome stability and genetic diseases.

More Related Videos

Genomic MRI - a Public Resource for Studying Sequence Patterns within Genomic DNA

Genomic MRI - a Public Resource for Studying Sequence Patterns within Genomic DNA

Published on: May 9, 2011

3D Multicolor DNA FISH Tool to Study Nuclear Architecture in Human Primary Cells

3D Multicolor DNA FISH Tool to Study Nuclear Architecture in Human Primary Cells

Published on: January 25, 2020

Related Experiment Videos

Last Updated: May 28, 2026

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.

Published on: May 6, 2010

Genomic MRI - a Public Resource for Studying Sequence Patterns within Genomic DNA

Genomic MRI - a Public Resource for Studying Sequence Patterns within Genomic DNA

Published on: May 9, 2011

3D Multicolor DNA FISH Tool to Study Nuclear Architecture in Human Primary Cells

3D Multicolor DNA FISH Tool to Study Nuclear Architecture in Human Primary Cells

Published on: January 25, 2020

Area of Science:

Genomics
Bioinformatics
Systems Biology

Background:

Genomes can be analyzed using multifractal formalisms.
Previous work applied multifractal analysis to the Caenorhabditis elegans genome.
This study investigates multifractality in the human genome.

Purpose of the Study:

To investigate multifractality in the human genome sequence.
To correlate genomic multifractality with specific DNA elements and features.
To propose a novel model for human genome structure and organization.

Main Methods:

Multifractal analysis of the human genome sequence.
Correlation analysis with genomic elements (Alu, CpG islands, G+C content, LINE, MIR, MER, LTRs).
Analysis of gene function, orthologous gene clusters, metabolic pathways, exons, and gene families in relation to multifractality.

Main Results:

The human genome sequence displays multifractality.
Multifractality strongly correlates with Alu elements, and to a lesser extent, CpG islands and G+C content.
Gene function, orthologous genes, pathways, exons, and large gene families show varied relationships with multifractality ranges, with a proposed multifractal map for human chromosomes.

Conclusions:

A descriptive non-linear model for human genome structure is proposed, characterized by multifractal regionalization.
This organization has implications for genome stability, gene regulation, and genetic diseases, particularly concerning Alu elements.
Quantifications are valuable for understanding genome stability, genetic diversity, adaptation, and phylogenetic analyses.