Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Viral Recombination

Viral Recombination

Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.

Viral Mutations

Viral Mutations

A mutation is a change in the sequence of bases of DNA or RNA in a genome. Some mutations occur during replication of the genome due to errors made by the polymerase enzymes that replicate DNA or RNA. Unlike DNA polymerase, RNA polymerase is prone to errors because it is not capable of “proofreading” its work. Viruses with RNA-based genomes, like HIV, therefore accrue mutations faster than viruses with DNA-based genomes. Because mutation and recombination provide the raw material for adaptive...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Resilience of precuneus neurotrophic signaling pathways despite amyloid pathology in prodromal Alzheimer's disease.

Biological psychiatry·2014

Same author

Magnetoacoustic tomography with magnetic induction for high-resolution bioimepedance imaging through vector source reconstruction under the static field of MRI magnet.

Medical physics·2014

Same author

Hollow superparamagnetic PLGA/Fe3O4 composite microspheres for lysozyme adsorption.

Nanotechnology·2014

Same author

[A bird's eye view of the algorithms and software packages for reconstructing phylogenetic trees].

Dong wu xue yan jiu = Zoological research·2014

Same author

Functional and biodegradable dendritic macromolecules with controlled architectures as nontoxic and efficient nanoscale gene vectors.

Biotechnology advances·2014

Same author

[Effects of artificial vegetation on the spatial heterogeneity of soil moisture and salt in coastal saline land of Chongming Dongtan, Shanghai].

Ying yong sheng tai xue bao = The journal of applied ecology·2014

Search research articles

Related Experiment Video

Updated: May 28, 2026

In Vitro Culture for H5N1-Specific Duck T Cells and Detection of Immune Responses Using Intracellular Cytokine Staining Method

In Vitro Culture for H5N1-Specific Duck T Cells and Detection of Immune Responses Using Intracellular Cytokine Staining Method

Published on: May 30, 2025

Tembusu virus in ducks, china.

Zhenzhen Cao¹, Cun Zhang, Yuehuan Liu

¹Key Laboratory of Zoonosis of Ministry of Agriculture, Beijing, People's Republic of China.

Emerging Infectious Diseases

|October 18, 2011

Summary

A flavivirus outbreak in Chinese egg-laying ducks in 2010 was identified as Tembusu virus. This mosquito-borne flavivirus, belonging to the Ntaya virus group, emerged in domestic ducks.

More Related Videos

Avian Influenza Surveillance with FTA Cards: Field Methods, Biosafety, and Transportation Issues Solved

Avian Influenza Surveillance with FTA Cards: Field Methods, Biosafety, and Transportation Issues Solved

Published on: August 2, 2011

Influenza Virus Propagation in Embryonated Chicken Eggs

Influenza Virus Propagation in Embryonated Chicken Eggs

Published on: March 19, 2015

Related Experiment Videos

Last Updated: May 28, 2026

In Vitro Culture for H5N1-Specific Duck T Cells and Detection of Immune Responses Using Intracellular Cytokine Staining Method

In Vitro Culture for H5N1-Specific Duck T Cells and Detection of Immune Responses Using Intracellular Cytokine Staining Method

Published on: May 30, 2025

Avian Influenza Surveillance with FTA Cards: Field Methods, Biosafety, and Transportation Issues Solved

Avian Influenza Surveillance with FTA Cards: Field Methods, Biosafety, and Transportation Issues Solved

Published on: August 2, 2011

Influenza Virus Propagation in Embryonated Chicken Eggs

Influenza Virus Propagation in Embryonated Chicken Eggs

Published on: March 19, 2015

Area of Science:

Veterinary Virology
Emerging Infectious Diseases
Molecular Epidemiology

Background:

Disease outbreaks in domestic poultry can pose significant economic and public health risks.
Flaviviruses are known to infect a wide range of hosts, including birds and mammals.
Tembusu virus (Tembusu) is a mosquito-borne flavivirus previously identified in Southeast Asia.

Purpose of the Study:

To investigate the etiological agent responsible for a disease outbreak in egg-laying ducks in China in 2010.
To characterize the isolated virus and determine its phylogenetic relationship to known flaviviruses.

Main Methods:

Viral isolation from affected ducks.
Partial genome sequencing of the isolated virus.
Phylogenetic analysis to compare the isolate with existing flavivirus strains.

Main Results:

A flavivirus was successfully isolated from egg-laying ducks during the 2010 outbreak in China.
Partial sequencing revealed 87%-91% nucleotide identity to known Tembusu virus strains.
Phylogenetic analysis placed the isolate within the Tembusu virus lineage of the Ntaya virus group.

Conclusions:

The findings confirm the emergence of Tembusu virus in a domestic duck population in China.
This study highlights the potential for Tembusu virus to adapt to and cause disease in avian hosts.
Surveillance for Tembusu virus in poultry populations is warranted to monitor its spread and impact.