Related Experiment Video
Updated: May 28, 2026
Experimental Model of Ligature-Induced Peri-Implantitis in Mice
Published on: May 17, 2024
Anchorage miniscrews: a histologic study of peri-implant soft tissue
Mourad Sebbar1, Farid Bourzgui, Latifa Badre
160, boulevard Moulay Ismail, résidence Zineb, 3(e) étage, n(o) 4, Casablanca, Morocco.
Introduction:
The aim of our study was to investigate the different histologic reactions of peri-implant soft tissue to miniscrews used in various orthodontic indications in patients during the course of treatment.
Material And Methods:
Our study focuses on patients receiving orthodontic treatment and in whom we placed anchorage miniscrews for various orthodontic indications. Twenty-eight miniscrews from the same manufacturer (Dual Top Anchor system(®), Korea) were studied. The soft tissue surrounding each miniscrew was sampled for histologic analysis.
Results:
All the peri-implant soft tissue samples displayed signs of inflammation. Each tissue sample exhibited either a moderately or highly inflamed surface epithelium and underlying connective tissue.
Discussion And Conclusion:
The variations in tissue response shown by the different human biopsies could be greater than those observed in standardized conditions in animal experiments. Interpretations regarding tissue response on a small number of human biopsies should be made cautiously. Nevertheless, this histological information is invaluable in order to validate and confirm the animal model.
