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Primary hyperparathyroidism in the underinsured: a study of 493 patients
Azad A Jabiev1, John I Lew, Jane L Garb
1Division of Endocrine Surgery, University of Miami, Miami, FL, USA.
Insights
Underinsured patients with primary hyperparathyroidism (HPT) present with higher calcium and PTH levels, more hypercalcemic crisis, and less follow-up. Health insurance coverage impacts HPT care disparities.
Area of Science:
- Endocrinology
- Health Services Research
Background:
- Disparities in primary hyperparathyroidism (HPT) care may exist.
- This study investigates the presentation and outcomes of underinsured patients undergoing parathyroidectomy.
Purpose of the Study:
- To examine the clinical characteristics and treatment outcomes of underinsured patients with HPT.
- To identify disparities in HPT care associated with insurance status.
Main Methods:
- A cohort of 493 HPT patients undergoing initial parathyroidectomy was divided into underinsured (n=94) and insured (n=399) groups.
- Univariate and multivariate analyses were performed to assess the association of underinsurance with clinical variables, adjusting for race and ethnicity.
Main Results:
- Underinsured patients were more likely to be of Black or Hispanic background (92% vs. 44%).
- Group 1 patients had higher mean preoperative serum calcium (12.1 vs. 11.8 mg/dL) and PTH levels (263 vs. 198 pg/mL).
- Underinsurance was associated with higher calcium levels (P=.011) and hypercalcemic crisis (OR, 5.59; P=.012). Shorter follow-up (15 vs. 24 months) and higher postoperative PTH levels (76 vs. 48 pg/mL) were observed in underinsured patients.
Conclusions:
- Underinsured patients with HPT exhibit distinct clinical presentations, including higher calcium and PTH levels and increased risk of hypercalcemic crisis.
- These patients are less likely to complete follow-up care.
- Underfunded health insurance coverage appears to be a significant factor contributing to observed disparities in HPT management.
Background:
Disparities may exist in the care of patients with primary hyperparathyroidism (HPT). This study examines the presentation and outcomes of underinsured patients undergoing parathyroidectomy.
Methods:
We divided 493 HPT patients who underwent initial parathyroidectomy from 2000 to 2008 at a single institution into 2 groups: underinsured patients (group 1; n = 94) evaluated and treated at a county hospital, and patients with insurance (group 2; n = 399). Univariate and multivariate analysis adjusting for race and ethnicity were conducted to determine the association of being underinsured with several clinical variables.
Results:
More patients in group 1 compared with group 2 were of black or Hispanic background (92% vs. 44%; P < .0001). Group 1 patients had higher mean preoperative serum calcium and PTH levels: 12.1 vs. 11.8 mg/dL (P = .009) and 263 vs. 198 pg/mL (P = .03), respectively. Seven group 1 (7.4%) and 7 group 2 (1.8%) patients presented with hypercalcemic crisis (P = .003). On multivariate analysis, underinsurance was associated with higher serum calcium levels (P = .011) and hypercalcemic crisis at presentation (odds ratio, 5.59; 95% confidence interval, 1.45-21.51; P = .012). Follow-up was shorter in group 1 patients (15 vs. 24 months; P < .001) and postoperative PTH levels were higher (76 vs. 48 pg/mL; P < .001). Other perioperative data were not different between the groups.
Conclusion:
Underinsured patients with HPT may present with higher serum calcium and PTH levels, are more likely to have hypercalcemic crisis, and less likely to return for follow-up. Underfunded health insurance coverage may account for differences seen in this study.
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