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Related Experiment Video

Updated: May 28, 2026

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives

Published on: September 16, 2021

Does emotional support during the luteal phase decrease the stress of in vitro fertilization?

Christine C Skiadas¹, Kathryn Terry, Mary De Pari

¹Department of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.

Fertility and Sterility

|October 18, 2011

Summary

This summary is machine-generated.

Phone calls did not significantly reduce stress for women undergoing their first in vitro fertilization (IVF) cycle. However, patients receiving emotional support found the intervention helpful during the waiting period for their pregnancy test.

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Area of Science:

Reproductive Medicine
Psychological Support in ART
Clinical Trial Methodology

Background:

The period between embryo transfer (ET) and pregnancy testing in assisted reproductive technology (ART) cycles is often associated with significant psychological stress.
Effective interventions to mitigate this stress are crucial for patient well-being during in vitro fertilization (IVF).

Purpose of the Study:

To evaluate the impact of phone calls from social workers on perceived stress levels in women undergoing their first fresh IVF cycle.
To assess patient-reported benefits and the perceived need for emotional support during the ET to pregnancy test waiting period.

Main Methods:

A randomized controlled trial was conducted at an academic medical center.
Participants were women undergoing a first fresh IVF cycle with autologous oocytes.
The intervention group received phone calls from social workers, while the control group received standard care.

Main Results:

No statistically significant difference in Perceived Stress Scale (PSS) scores or changes in PSS scores was observed between the intervention and control groups.
A higher percentage of patients in the intervention group reported that participating in the study was helpful (65.9% vs. 21.4%).
The intervention group was more likely to recommend emotional support during an IVF cycle (95.4% vs. 78.6%).

Conclusions:

While phone calls did not significantly reduce objective stress measures (PSS scores), patients perceived them as beneficial.
There is a clear patient-reported need for enhanced emotional support during the waiting period between ET and pregnancy testing in IVF.
Further research is warranted to identify optimal interventions for psychological support during this critical phase of fertility treatment.