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Endocarditis and hip arthritis associated with Scedosporium inflatum
E C Toy1, M G Rinaldi, C B Savitch
1Office of Medical Education, Ventura County Medical Center, Calif.
Abstract:
A 30-year-old man had endocarditis and hip arthritis associated with the recently recognized fungus, Scedosporium inflatum. Inhibition, and possibly cure, of endocarditis occurred with medical therapy alone. Data from in vitro susceptibility testing did not predict clinical response. This case also illustrates the need to standardize fungal susceptibility testing and to remain vigilant for emerging pathogens.
Insights
A fungal infection caused by Scedosporium inflatum led to endocarditis and hip arthritis. Medical therapy alone inhibited the infection, but in vitro susceptibility testing did not predict the clinical outcome.
Area of Science:
- Mycology
- Infectious Diseases
- Rheumatology
Background:
- Emerging fungal pathogens pose a growing threat in clinical settings.
- Scedosporium inflatum is a recently identified fungus with potential for causing severe infections.
- Infections involving multiple organ systems, such as endocarditis and arthritis, require prompt diagnosis and management.