Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Nature and Nurture01:10

Nature and Nurture

Many human characteristics, like height, are shaped by both nature—in other words, by our genes—and by nurture, or our environment. For example, chronic stress during childhood inhibits the production of growth hormones and consequently reduces bone growth and height. Scientists estimate that 70-90% of variation in height is due to genetic differences among individuals, and 10-30% of variation in height is due to differences in the environments that individuals experience, such as differences...
Mouse Models of Cancer Study02:43

Mouse Models of Cancer Study

Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
Toxicity Testing in Animals01:23

Toxicity Testing in Animals

Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...
Preclinical Development: Overview01:28

Preclinical Development: Overview

Preclinical development consists of a series of tests that ensure the safety and efficacy of a new therapeutic compound before it is tested in humans. There are four main phases to this process. First, safety pharmacology tests are conducted to ensure the drug does not produce any acutely harmful effects. These tests examine parameters such as bronchoconstriction, cardiac dysrhythmias, blood pressure changes, and ataxia. Next, preliminary toxicological testing is performed to determine the...
Oxygen Requirements and Growth Patterns01:29

Oxygen Requirements and Growth Patterns

Microorganisms exhibit diverse oxygen requirements and growth patterns driven by their metabolic strategies and environmental adaptations. Oxygen, while essential for many organisms, can also be toxic under certain conditions, shaping how microorganisms grow and survive.Oxygen Requirements of MicroorganismsMicroorganisms are classified based on their ability to use or tolerate oxygen:● Obligate aerobes like Mycobacterium tuberculosis need oxygen for energy production, as it serves as the...
Growth of Cartilage and Bone Tissue01:27

Growth of Cartilage and Bone Tissue

Chondrocytes form a temporary cartilaginous model by dividing and secreting a thick gel-like extracellular matrix. Once the chondrocytes undergo programmed cell death, osteoblasts enter the site of the cartilaginous model. The process of replacing the temporary cartilaginous model with bone in an ordered manner is called endochondral ossification. In endochondral ossification, not all of the cartilage is replaced by bone tissue. Some cartilage that performs a protective and supportive function...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effects of Extremely Low Frequency Magnetic Field Exposure (50 Hz, 200 µT) on Cell Viability, DNA Damage and Micronucleus Formation of Human Skin Cells.

Bioelectromagnetics·2026
Same author

5G-exposed human skin cells do not respond with altered gene expression and methylation profiles.

PNAS nexus·2025
Same author

Design and Dosimetric Characterization of a Broadband Exposure Facility for In Vitro Experiments in the Frequency Range 18-40.5 GHz.

Bioelectromagnetics·2021
Same author

Spermatogenesis in the Roborovski hamster (Phodopus roborovskii) and the Chinese hamster (Cricetulus griseus).

Andrology·2021
Same author

Effects of Long-Term Exposure of Intermediate Frequency Magnetic Fields (20 kHz, 360 µT) on the Development, Pathological Findings, and Behavior of Female Mice.

Bioelectromagnetics·2021
Same author

No Increased DNA Damage Observed in the Brain, Liver, and Lung of Fetal Mice Treated With Ethylnitrosourea and Exposed to UMTS Radiofrequency Electromagnetic Fields.

Bioelectromagnetics·2020

Related Experiment Video

Updated: May 28, 2026

Real Time and Repeated Measurement of Skeletal Muscle Growth in Individual Live Zebrafish Subjected to Altered Electrical Activity
11:41

Real Time and Repeated Measurement of Skeletal Muscle Growth in Individual Live Zebrafish Subjected to Altered Electrical Activity

Published on: June 16, 2022

Animal studies on growth and development.

Alexander Lerchl1

  • 1Jacobs University Bremen, School of Engineering and Science, Research II, Bremen, Germany. a.lerchl@jacobs-university.de

Progress in Biophysics and Molecular Biology
|October 18, 2011
PubMed
Summary
This summary is machine-generated.

Extensive animal studies show no adverse health effects from electromagnetic fields below exposure limits. Even high-level, long-term exposure in mice did not impact development or fertility, suggesting low risk for humans.

More Related Videos

Culturing and Measuring Fetal and Newborn Murine Long Bones
06:58

Culturing and Measuring Fetal and Newborn Murine Long Bones

Published on: April 26, 2019

Protocol for Assessing the Relative Effects of Environment and Genetics on Antler and Body Growth for a Long-lived Cervid
09:09

Protocol for Assessing the Relative Effects of Environment and Genetics on Antler and Body Growth for a Long-lived Cervid

Published on: August 8, 2017

Related Experiment Videos

Last Updated: May 28, 2026

Real Time and Repeated Measurement of Skeletal Muscle Growth in Individual Live Zebrafish Subjected to Altered Electrical Activity
11:41

Real Time and Repeated Measurement of Skeletal Muscle Growth in Individual Live Zebrafish Subjected to Altered Electrical Activity

Published on: June 16, 2022

Culturing and Measuring Fetal and Newborn Murine Long Bones
06:58

Culturing and Measuring Fetal and Newborn Murine Long Bones

Published on: April 26, 2019

Protocol for Assessing the Relative Effects of Environment and Genetics on Antler and Body Growth for a Long-lived Cervid
09:09

Protocol for Assessing the Relative Effects of Environment and Genetics on Antler and Body Growth for a Long-lived Cervid

Published on: August 8, 2017

Area of Science:

  • Environmental Health
  • Toxicology
  • Bioelectromagnetics

Background:

  • No established biological mechanism explains adverse health effects from electromagnetic fields (EMF) below regulatory limits.
  • Previous studies on EMF effects in developing animals often had methodological limitations, such as thermal artifacts.

Purpose of the Study:

  • To investigate potential adverse health effects of electromagnetic field exposure on animal growth and development.
  • To assess carcinogenic or co-carcinogenic effects and general developmental impacts of EMF exposure in animal models.

Main Methods:

  • Review of existing literature on EMF effects in animal models (mice, rats).
  • Analysis of studies employing sophisticated exposure devices to mitigate thermal effects.
  • Description of ongoing experiments involving chronic head-only EMF exposure in rats from early age.

Main Results:

  • The vast majority of reviewed publications show no adverse effects from EMF exposure.
  • A large-scale study in mice exposed to UMTS signals (1.3 W/kg SAR) for four generations found no systematic alterations in development or fertility.
  • Ongoing rat studies involve behavioral testing across different age groups to assess brain development impacts.

Conclusions:

  • Current evidence strongly suggests that electromagnetic fields below recommended exposure limits are unlikely to cause adverse health effects in humans.
  • Robust animal studies, even at high exposure levels, support the safety of EMF exposure within established guidelines.
  • Further research is ongoing to comprehensively understand potential subtle effects on brain development.