Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Fusion of Secretory Vesicles with the Plasma Membrane

Fusion of Secretory Vesicles with the Plasma Membrane

Proteins and neurotransmitters in secretory vesicles can be released from a cell upon vesicle docking, priming, and fusion with the plasma membrane. Vesicles are docked and primed in preparation for the quick exocytosis of their contents in response to a stimulus. The fusion process is mainly carried out by a SNAP Receptor or SNARE complex, consisting of synaptobrevin, syntaxin-1, and SNAP-25.
In 1993, Jim Rothman proposed that the antiparallel pairing of vesicular and transmembrane SNAREs, or...

Modified-Release Drug Delivery Systems: Stimuli-Activated

Modified-Release Drug Delivery Systems: Stimuli-Activated

Stimuli-activated drug delivery systems are designed to release drugs in response to specific physical, chemical, or biological stimuli. These systems often utilize hydrogels—three-dimensional, hydrophilic polymer networks capable of swelling in aqueous environments and retaining significant fluid volumes. Upon exposure to particular stimuli, these hydrogels undergo structural transitions that allow the embedded drug to be released. Due to this adaptive behavior, such systems are also called...

Clathrin Coated Vesicles

Clathrin Coated Vesicles

Clathrin-coated vesicles use endocytosis to transport receptors and lysosomal hydrolases from the Golgi to the lysosome in the late secretory pathway. Clathrin-mediated endocytosis was the first described endocytic process, and Clathrin-coated vesicles remain one of the most well-studied transport vesicles. The molecular machinery that generates clathrin-coated vesicles comprises over 50 proteins that precisely coordinate vesicle formation. Cell surface receptors concentrated in indented sites...

COP Coated Vesicles

COP Coated Vesicles

Membrane-enclosed structures called vesicles transport proteins and lipids across the cell. The vesicles derive their cargo from the plasma membrane, Golgi, ER, or endosome. Coated vesicles are spherical, protein-coated carriers with a 50–100 nm diameter that mediate bidirectional transport between the ER and the Golgi. The distribution of proteins between the ER and Golgi complex is dynamic and is maintained by different coated vesicles. Their formation is driven by the assembly of different...

Exocytosis

Exocytosis

Exocytosis is used to release material from cells. Like other bulk transport mechanisms, exocytosis requires energy.

Exocytosis

Exocytosis

Exocytosis is a process that releases molecules outside the cell. Like other bulk transport mechanisms, exocytosis requires energy.
Exocytosis is the opposite of endocytosis, which brings molecules inside the cell. Sometimes, the released materials are signaling molecules. For example, neurons typically use exocytosis to release neurotransmitters. Cells also use exocytosis to insert proteins such as ion channels into their cell membranes, secrete proteins for use in the extracellular matrix, or...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

ZmAGO18b negatively regulates maize resistance against southern leaf blight.

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·2023

Same author

Active-ion-gated room temperature acetone gas sensing of ZnO nanowires array.

Exploration (Beijing, China)·2023

Same author

Three neutralizing mAbs induced by MPXV A29L protein recognizing different epitopes act synergistically against orthopoxvirus.

Emerging microbes & infections·2023

Same author

Cobalt/aluminum co-substitution in a LiNi

Chemical communications (Cambridge, England)·2023

Same author

Regulatory mechanisms and clinical applications of tumor-driven exosomal circRNAs in cancers.

International journal of medical sciences·2023

Same author

The mechanism of white flower formation in Brassica rapa is distinct from that in other Brassica species.

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·2023

Search research articles

Related Experiment Video

Updated: May 28, 2026

Automated Detection and Analysis of Exocytosis

Automated Detection and Analysis of Exocytosis

Published on: September 11, 2021

K(+)-recognition capsules with squirting release mechanisms.

Zhuang Liu¹, Li Liu, Xiao-Jie Ju

¹School of Chemical Engineering, Sichuan University, Chengdu, Sichuan, 610065, China.

Chemical Communications (Cambridge, England)

|October 18, 2011

Summary

New smart capsules recognize potassium ions (K(+)) and rapidly shrink, squirting out oil. This host-guest complexation and phase transition system offers a novel approach for K(+) sensing applications.

More Related Videos

Preparation of Multifunctional Silk-Based Microcapsules Loaded with DNA Plasmids Encoding RNA Aptamers and Riboswitches

Preparation of Multifunctional Silk-Based Microcapsules Loaded with DNA Plasmids Encoding RNA Aptamers and Riboswitches

Published on: October 8, 2021

A "Plug-And-Display" Nanoparticle Vaccine Platform Based on Outer Membrane Vesicles Displaying SARS-CoV-2 Receptor-Binding Domain

A "Plug-And-Display" Nanoparticle Vaccine Platform Based on Outer Membrane Vesicles Displaying SARS-CoV-2 Receptor-Binding Domain

Published on: July 25, 2022

Related Experiment Videos

Last Updated: May 28, 2026

Automated Detection and Analysis of Exocytosis

Automated Detection and Analysis of Exocytosis

Published on: September 11, 2021

Preparation of Multifunctional Silk-Based Microcapsules Loaded with DNA Plasmids Encoding RNA Aptamers and Riboswitches

Preparation of Multifunctional Silk-Based Microcapsules Loaded with DNA Plasmids Encoding RNA Aptamers and Riboswitches

Published on: October 8, 2021

A "Plug-And-Display" Nanoparticle Vaccine Platform Based on Outer Membrane Vesicles Displaying SARS-CoV-2 Receptor-Binding Domain

A "Plug-And-Display" Nanoparticle Vaccine Platform Based on Outer Membrane Vesicles Displaying SARS-CoV-2 Receptor-Binding Domain

Published on: July 25, 2022

Area of Science:

Materials Science
Supramolecular Chemistry
Chemical Engineering

Background:

Potassium ion (K(+)) detection is crucial in various fields, including environmental monitoring and biological sensing.
Developing smart materials that respond to specific ion concentrations is an ongoing challenge in materials science.

Purpose of the Study:

To engineer K(+)-recognition capsules that translate ion detection into a measurable physical response.
To investigate the mechanisms underlying the capsule's response to K(+).

Main Methods:

Development of novel capsules utilizing host-guest complexation and phase transition properties.
Experimental validation of K(+)-induced capsule shrinkage and oil core ejection.

Main Results:

The developed capsules exhibit rapid shrinkage and squirting release of encapsulated oil upon encountering K(+).
The observed phenomenon is driven by the synergistic effects of host-guest interactions and membrane phase transitions.
The system demonstrates a functional translation of K(+)-recognition into a squirting release mechanism.

Conclusions:

The K(+)-recognition capsules represent a promising smart functional system for ion sensing.
This work provides a foundation for designing advanced responsive materials based on ion-triggered physical transformations.