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Related Concept Videos

Neuroplasticity01:01

Neuroplasticity

Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.
Neuronal Communication01:28

Neuronal Communication

Neurons, the fundamental units of the brain and nervous system, communicate through complex electrochemical signals that underpin all cognitive and bodily functions. This communication is primarily facilitated by a process involving the generation and propagation of an action potential along the axon of the neuron. When the internal electrical charge of a neuron surpasses a certain threshold, an action potential is triggered. This rapid change in voltage travels swiftly along the axon to the...
Overview of Synapses01:25

Overview of Synapses

A synapse is a specialized structure where two neurons connect, allowing them to pass an electrical or chemical signal to another neuron. It is the point of communication between neurons. The term "synapse" is derived from the Greek word "synapsis," which means "conjunction." The entire process of neural communication revolves around the synapse. When activated, a neuron releases chemicals known as neurotransmitters into the synapse. These neurotransmitters cross the synapse and bind to...
Long-term Potentiation01:25

Long-term Potentiation

Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
Hebbian LTP
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Long-term Potentiation01:35

Long-term Potentiation

Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre- and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
The Synapse02:47

The Synapse

Neurons communicate with one another by passing on their electrical signals to other neurons. A synapse is the location where two neurons meet to exchange signals. At the synapse, the neuron that sends the signal is called the presynaptic cell, while the neuron that receives the message is called the postsynaptic cell. Note that most neurons can be both presynaptic and postsynaptic, as they both transmit and receive information.

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Related Experiment Video

Updated: May 28, 2026

Optogenetic Entrainment of Hippocampal Theta Oscillations in Behaving Mice
07:33

Optogenetic Entrainment of Hippocampal Theta Oscillations in Behaving Mice

Published on: June 29, 2018

Neural oscillations and information flow associated with synaptic plasticity.

Tao Zhang1

  • 1College of Life Sciences, Nankai University, Tianjin, China. zhangtao@nankai.edu.cn

Sheng Li Xue Bao : [Acta Physiologica Sinica]
|October 18, 2011
PubMed
Summary

Neural oscillations, rhythmic electrical activity in the brain, are key to understanding learning and memory. New algorithms analyzing neural information flow (NIF) offer insights into synaptic plasticity.

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Area of Science:

  • Neuroscience
  • Cognitive Science

Background:

  • Neural oscillations are rhythmic electrical activity present throughout the nervous system.
  • These oscillations, particularly in theta and gamma bands, are linked to cognitive functions like learning and memory.

Purpose of the Study:

  • To review evidence linking synchronous neural oscillations to cognitive processes.
  • To introduce novel algorithms for analyzing neural oscillations.
  • To present neural information flow (NIF) as a measure of synaptic plasticity.

Main Methods:

  • Review of existing literature on neural oscillations and cognitive processes.
  • Introduction of new analytical algorithms for neural oscillations.
  • Application of these algorithms to measure neural information flow (NIF).

Main Results:

  • Synchronous neural oscillations in theta and gamma bands correlate with learning and memory.
  • Novel algorithms provide a directionality index of neural information flow (NIF).
  • NIF serves as a quantifiable measure of synaptic plasticity.

Conclusions:

  • Neural oscillations are fundamental to cognitive processes.
  • Advanced analytical algorithms can elucidate the dynamics of neural information flow.
  • This approach offers a new method for studying synaptic plasticity.