Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cerebral Hemispheres01:05

Cerebral Hemispheres

The human brain, a complex organ, is functionally divided into two cerebral hemispheres—left and right. These hemispheres are interconnected by a structure of paramount importance, the corpus callosum. This substantial bundle of neural fibers is not just a bridge between the hemispheres but a crucial element for the brain's comprehensive functioning. It enables efficient communication between the two hemispheres, allowing each side of the brain to control and receive sensory and motor...
Somatosensory, Motor, and Association Cortex01:23

Somatosensory, Motor, and Association Cortex

The somatosensory cortex in the parietal lobes is crucial for interpreting sensory data such as touch, temperature, and proprioception. The somatosensory cortex, situated in the parietal lobes, plays a vital role in interpreting sensory information like touch, temperature, and proprioception—awareness of body position. This specialized brain region features an organized structure wherein neurons at the top primarily process sensations originating from the lower body. In contrast, those at the...
Cerebrum: Anatomical Overview II01:11

Cerebrum: Anatomical Overview II

Each cerebral hemisphere can be divided into three main regions. The outermost region, the cerebral cortex, is a thin layer (2 to 4 millimeters thick) made up of gray matter, consisting of neuron cell bodies, dendrites, glial cells, and blood vessels. The middle region, or white matter, is primarily composed of myelinated nerve fibers organized into three types of large tracts: association fibers, commissures, and projection fibers. Association fibers connect different areas within the same...
Lateralization01:28

Lateralization

Brain lateralization refers to the division of mental processes and functions between the two hemispheres of the brain, a phenomenon that optimizes neural efficiency and underpins complex abilities in humans. This specialization allows each hemisphere to perform tasks where it has a comparative advantage, facilitating more refined cognitive capabilities across different domains.
Diencephalon: Anatomical Regions01:30

Diencephalon: Anatomical Regions

The diencephalon, etymologically translated as 'through brain,' plays an integral role as the conduit between the cerebrum and the vast extent of the nervous system. However, the olfactory system is an exception, as it interfaces directly with the cerebrum. The diencephalon, deeply ensconced beneath the cerebrum, primarily consists of three paired structures — the thalamus, hypothalamus, and epithelamus. It also includes accessory structures such as the subthalamus, which houses the subthalamic...
Association Areas of the Cortex01:21

Association Areas of the Cortex

Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Comparative Study of IVIM-MRI Fitting Techniques in Glioma Grading: Conventional, Bayesian, and Voxel-Wise and Spatially-Aware Deep Learning Approaches.

Journal of magnetic resonance imaging : JMRI·2026
Same author

Enhancing efficiency in pediatric brain tumor segmentation using a pathologically diverse single-center clinical dataset.

Neuro-oncology advances·2026
Same author

Listening Without the Noise: Near-Silent Looping Star fMRI Reveals Neural Processing of Degraded Speech.

Human brain mapping·2026
Same author

The 2024 Brain Tumor Segmentation Challenge Meningioma Radiotherapy (BraTS-MEN-RT) dataset.

Scientific data·2026
Same author

Advances in automated fetal brain MRI segmentation and biometry: Insights from the FeTA 2024 challenge.

Medical image analysis·2026
Same author

Towards contrast- and pathology-agnostic clinical fetal brain MRI segmentation using SynthSeg.

NeuroImage·2026

Related Experiment Video

Updated: May 28, 2026

Using Informational Connectivity to Measure the Synchronous Emergence of fMRI Multi-voxel Information Across Time
07:12

Using Informational Connectivity to Measure the Synchronous Emergence of fMRI Multi-voxel Information Across Time

Published on: July 1, 2014

Connectivity-based parcellation reveals interhemispheric differences in the insula.

András Jakab1, Péter P Molnár, Péter Bogner

  • 1Department of Biomedical Laboratory and Imaging Science, Faculty of Medicine, University of Debrecen Medical and Health Science Center, 98. Nagyerdei krt., Debrecen 4032, Hungary. jakaba@med.unideb.hu

Brain Topography
|October 18, 2011
PubMed
Summary

This study used diffusion tractography to map human insular cortex connectivity, revealing subdivisions independent of traditional anatomy. Findings suggest a leftward functional dominance in the anterior insula, impacting its connectivity patterns.

More Related Videos

Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms
08:36

Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms

Published on: March 21, 2019

Modeling the Functional Network for Spatial Navigation in the Human Brain
05:55

Modeling the Functional Network for Spatial Navigation in the Human Brain

Published on: October 13, 2023

Related Experiment Videos

Last Updated: May 28, 2026

Using Informational Connectivity to Measure the Synchronous Emergence of fMRI Multi-voxel Information Across Time
07:12

Using Informational Connectivity to Measure the Synchronous Emergence of fMRI Multi-voxel Information Across Time

Published on: July 1, 2014

Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms
08:36

Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms

Published on: March 21, 2019

Modeling the Functional Network for Spatial Navigation in the Human Brain
05:55

Modeling the Functional Network for Spatial Navigation in the Human Brain

Published on: October 13, 2023

Area of Science:

  • Neuroimaging
  • Neuroanatomy
  • Connectomics

Background:

  • The insular cortex is crucial for interoception and emotion processing.
  • Its complex connectivity patterns remain incompletely understood.
  • Understanding insular organization is key to deciphering its role in various cognitive functions.

Purpose of the Study:

  • To investigate the organizational principles of the human insular cortex.
  • To delineate subdivisions based on shared remote projection patterns using diffusion tractography.
  • To explore potential hemispheric asymmetries in insular connectivity.

Main Methods:

  • Probabilistic diffusion tractography was applied to 40 healthy subjects.
  • Insular cortical masks were used to initiate fibertracking.
  • K-means clustering partitioned insular voxels based on connection similarity, followed by volumetric analysis.

Main Results:

  • Connectivity-based subdivisions did not align with known cytoarchitectural or gyral anatomy.
  • Significant interhemispheric asymmetry was observed, suggesting leftward functional dominance of the anterior insula.
  • Higher mean diffusivity was noted in the anterior insula bilaterally, without significant differences in fractional anisotropy.

Conclusions:

  • Insular cortex organization is primarily defined by its connectional topography rather than traditional anatomical boundaries.
  • The observed asymmetry points to lateralized functional roles, particularly in the anterior insula.
  • Diffusion MRI metrics suggest distinct microstructural properties in the anterior insula, potentially related to its functional specialization.