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Neonatal meningitis caused by Streptococcus gallolyticus subsp. pasteurianus

Maki Nagamatsu1, Taeko Takagi, Tadatomo Ohyanagi

  • 1Department of Clinical Laboratory, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-ku, Kawasaki, Kanagawa 216-8511, Japan. m-naga.7122@marianna-u.ac.jp

Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy
|October 18, 2011
PubMed

Insights

This report details a rare case of neonatal meningitis caused by Streptococcus gallolyticus subsp. pasteurianus in an 8-day-old infant. Prompt diagnosis and tailored antibiotic treatment led to the infant's successful recovery and discharge.

Area of Science:

  • Neonatal infectious diseases
  • Bacteriology
  • Clinical microbiology

Background:

  • Neonatal meningitis poses a significant threat to infant health.
  • Streptococcus gallolyticus subsp. pasteurianus is an emerging pathogen in neonatal infections.
  • Accurate identification and susceptibility testing are crucial for effective treatment.

Observation:

  • An 8-day-old male infant presented with symptoms suggestive of meningitis.
  • Cerebrospinal fluid analysis revealed Gram-positive cocci.
  • 16S rRNA sequencing confirmed the presence of Streptococcus gallolyticus subsp. pasteurianus.

Findings:

  • The infant was diagnosed with bacterial meningitis caused by S. gallolyticus subsp. pasteurianus.
  • Initial ampicillin therapy was augmented with panipenem/betamipron due to suspected inflammatory progression.
  • The infant showed a positive response to the antibiotic regimen and was discharged.

Implications:

  • This case highlights the importance of considering S. gallolyticus subsp. pasteurianus in neonatal meningitis.
  • Early and appropriate antimicrobial intervention is key to favorable outcomes.
  • Further research into the pathogenicity and treatment of this bacterium in neonates is warranted.

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