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Updated: May 28, 2026

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
Published on: January 15, 2022
A fluid?structure interaction study on the biomechanical behaviour of a curved artery with flexible wall
1Biomechanical Research Laboratory, College of Mechanical Engineering and Applied Electronics Technology, Beijing University of Technology, No. 100 Pingleyuan, Chaoyang District, Beijing, PR China. pandaxhw@sina.com
Abstract:
Research has shown that thrombus, stenosis, aneurysm, atherosclerosis and other vascular diseases are likely to occur in curved arteries such as aortic arch, coronary artery and cerebral artery. It is found that fatigue damage and failure of arteries are closely associated with the dynamic physiological environment where the arteries are situated. Based on these considerations, the behaviour of curved arteries subjected to a physiological environment is presented in this paper. The fluid-structure interaction (FSI) effect is considered. Wall stress distribution and its variation over time are investigated. Artery deformation regularity throughout the cardiac cycle has been analysed. It is believed that this study may provide insights into clinical research in the future.
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