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Relationship between left ventricular diastolic dysfunction and six minute walk test in patients with systemic
Ali Akdogan1, Ergun B Kaya, Abdurrahman Sahin
1Division of Rheumatology, Faculty of Medicine School of Physical Therapy and Rehabilitation, Hacettepe University, Ankara, Turkey.
Left ventricular diastolic dysfunction (LVDD) reduces functional capacity in systemic sclerosis (SSc) patients, as measured by the six-minute walk test (6MWT). Reduced 6MWT distance in SSc patients warrants investigation for LVDD.
Area of Science:
- Cardiology
- Rheumatology
- Pulmonology
Background:
- The six-minute walk test (6MWT) assesses functional capacity in cardiopulmonary diseases.
- Left ventricular diastolic dysfunction (LVDD) is a common cardiac issue in systemic sclerosis (SSc).
Purpose of the Study:
- To determine the impact of LVDD on 6MWT parameters in SSc patients.
Main Methods:
- 45 SSc patients were evaluated using the 6MWT.
- Exclusion criteria targeted conditions affecting 6MWT distance (6MWD).
- LVDD was assessed via echocardiography and categorized.
Main Results:
- 12% of SSc patients had LVDD and were older than those without.
- SSc patients with LVDD exhibited a shorter 6MWD (438.0 m vs. 506.0 m).
- A significant difference was observed in the percentage of predicted 6MWD between groups.
Conclusions:
- LVDD presence negatively impacts 6MWD in SSc patients.
- A decreased 6MWD in SSc patients suggests the need for LVDD evaluation.
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