Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

Ophthalmic Drug Delivery Systems

Ophthalmic Drug Delivery Systems

Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Nanoparticle-mediated inhibition of Yes-associated protein prevents corneal scarring after traumatic injury.

Materials today. Bio·2026

Same author

Ophthalmologic assessment and intracranial pressure in children: diagnostic methods, clinical correlations, and future directions.

Frontiers in pediatrics·2026

Same author

Topical Losartan in Ophthalmology: Rationale, Experimental and Clinical Evidence, and Emerging Clinical Applications.

Journal of clinical medicine·2026

Same author

MPox virus transmission to healthcare worker in Europe.

Enfermedades infecciosas y microbiologia clinica (English ed.)·2026

Same author

Management of persistent corneal epithelial defects: role of insulin.

Current opinion in ophthalmology·2026

Same author

Ophthalmological involvement in monkeypox during the European outbreak: A case series.

European journal of ophthalmology·2026

Search research articles

Related Experiment Video

Updated: May 28, 2026

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Published on: January 26, 2018

[Simulation in ophthalmology].

Ana M Muñoz-Hernández¹, Rocío García-Catalán, Enrique Santos-Bueso

¹Unidad de Neurooftalmología, Hospital Clínico San Carlos, Madrid, España. ammh.humanes@yahoo.es

Archivos De La Sociedad Espanola De Oftalmologia

|October 19, 2011

Summary

This summary is machine-generated.

Ophthalmologists encountered four patients with simulated visual loss. Comprehensive testing revealed no organic cause, indicating non-organic visual disturbances are common in eye care.

More Related Videos

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Published on: January 12, 2022

Related Experiment Videos

Last Updated: May 28, 2026

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Published on: January 26, 2018

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Published on: January 12, 2022

Area of Science:

Ophthalmology
Psychosomatic Medicine

Background:

Non-organic visual loss presents a diagnostic challenge in ophthalmology.
Understanding the underlying causes, whether conscious simulation or psychosocial factors, is crucial for effective patient management.

Observation:

Four distinct cases of simulated ophthalmological symptoms were reported.
Patients included children and adults presenting with varied visual complaints like bilateral visual loss and decreased visual acuity.
Thorough structural and functional eye examinations yielded no pathological findings in any patient.

Findings:

All four cases were diagnosed with simulated ophthalmological symptoms.
Adult simulation often involves conscious attempts to gain benefit, while pediatric cases are linked to psychosocial and psychiatric issues.

Implications:

This highlights the importance of considering non-organic causes in visual disturbances.
Accurate diagnosis of simulated visual loss requires a multidisciplinary approach, integrating ophthalmological and psychological assessments.
Recognizing these cases can prevent unnecessary investigations and guide appropriate supportive care.