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Related Concept Videos

Intestinal Obstruction II: Pathophysiology01:07

Intestinal Obstruction II: Pathophysiology

Intestinal obstruction triggers a series of physiological responses, starting with gas and fluid accumulation in the bowel segment proximal to the obstruction, leading to distension. This distended intestine compresses the diaphragm, hindering lung expansion and potentially leading to reduced respiratory effort, atelectasis, and pneumonia.To overcome the blockage, the gut intensifies contractions, causing colicky abdominal pain, nausea, and vomiting, which reduces fluid and food intake and...
Intestinal Obstruction I: Introduction01:29

Intestinal Obstruction I: Introduction

Intestinal obstruction is a partial or complete blockage of the small or large intestine that disrupts the normal flow of intestinal contents through the lumen. This interruption impairs digestion, absorption, and fluid balance, and may lead to serious complications if not treated promptly.Mechanical ObstructionMechanical obstruction occurs when a physical blockage prevents intestinal contents from passing, arising from within the lumen or the bowel wall, or from external compression.Adhesions,...
Appendicitis01:19

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
Bacterial Gastroenteritis01:18

Bacterial Gastroenteritis

Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...

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Related Experiment Video

Updated: May 28, 2026

Intestinal Epithelial Regeneration in Response to Ionizing Irradiation
09:10

Intestinal Epithelial Regeneration in Response to Ionizing Irradiation

Published on: July 27, 2022

Acute radiation enteritis causing small bowel obstruction.

N J Curtis1, T Bryant, S Raj

  • 1University Surgical Unit, Level F Centre Block, Southampton University Hospitals NHS Trust, Southampton, UK. nathancurtis@doctors.org.uk

Annals of the Royal College of Surgeons of England
|October 19, 2011
PubMed
Summary
This summary is machine-generated.

Acute radiation enteritis can cause small bowel obstruction, a complication less understood than late side effects. Clinicians must recognize this acute radiation complication as radiotherapy use expands.

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Last Updated: May 28, 2026

Intestinal Epithelial Regeneration in Response to Ionizing Irradiation
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Rodent Model of Intestinal Ischemia-Reperfusion Injury via Occlusion of the Superior Mesenteric Artery
06:29

Rodent Model of Intestinal Ischemia-Reperfusion Injury via Occlusion of the Superior Mesenteric Artery

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Area of Science:

  • Oncology
  • Gastroenterology
  • Radiotherapy

Background:

  • While late intestinal side effects of radiation are well-documented, acute complications remain underreported.
  • Radiotherapy is increasingly utilized in cancer management, necessitating a comprehensive understanding of its adverse effects.

Observation:

  • A case of small bowel obstruction secondary to acute radiation enteritis is presented.
  • This highlights a significant, yet less commonly discussed, immediate complication of radiation therapy.

Findings:

  • Acute radiation enteritis can manifest as a small bowel obstruction.
  • This condition requires clinical vigilance despite the focus on long-term sequelae.

Implications:

  • Clinicians must be aware of acute radiation enteritis as a potential complication.
  • Early recognition and management are crucial for patients undergoing radiotherapy.
  • Further research into acute radiation enteritis is warranted to improve patient outcomes.