Related Experiment Video
Updated: Aug 10, 2026

A Coupled Experiment-finite Element Modeling Methodology for Assessing High Strain Rate Mechanical Response of Soft Biomaterials
Published on: May 18, 2015
Interaction of penetrating missiles with tissues: some common misapprehensions and implications for wound management
1Ministry of Defence, Medical Division, Chemical Defence Establishment, Porton, Salisbury, UK.
Abstract:
It is apparent from review of published papers and books that misunderstanding and confusion exists in the minds of many authors describing the interaction of penetrating missiles with tissues. These misapprehensions may influence the management of wounds by suggesting didactic approaches based upon a preconceived notion of the nature and severity of the wound for different types of projectiles. This review considers the biophysics of penetrating missile wounds, highlights some of the more common misconceptions and seeks to reconcile the conflicting and confusing management doctrines that are promulgated in the literature-differences that arise not only from two scenarios, peace and war, but also from misapprehensions of the wounding process. Wounds of war and of peacetime differ both in the nature of the wound and in the propensity for wound infection. Additionally, the limitations imposed by war dictate the type of management that may be practised and result in procedures that would be considered inappropriate by some in civilian clinical practice. Many of the procedures described in civilian peacetime settings, such as reliance on antibiotics alone for the control of infection in penetrating wounds, or minimal excision and debridement, can yield good results but would herald disaster if transposed to a war setting.
Insights
Misconceptions about missile-tissue interactions can lead to inappropriate wound management. This review clarifies the biophysics of penetrating wounds, differentiating war and peace scenarios for better treatment strategies.
Area of Science:
- Biophysics
- Trauma Surgery
- Wound Management
Background:
- Widespread misunderstanding exists regarding the interaction of penetrating missiles with tissues.
- This confusion influences wound management strategies, potentially leading to inappropriate treatment approaches based on projectile type.
- Conflicting doctrines in the literature arise from differing scenarios (war vs. peace) and misinterpretations of the wounding process.
Purpose of the Study:
- To review the biophysics of penetrating missile wounds.
- To highlight common misconceptions in wound management literature.
- To reconcile conflicting management doctrines for penetrating wounds in different settings.
Main Methods:
- Literature review of published papers and books on missile-tissue interactions and wound management.
- Analysis of biophysical principles governing penetrating injuries.
- Comparative assessment of wound management strategies in war and peacetime.
Main Results:
- Penetrating missile wounds exhibit distinct characteristics in war and peacetime, particularly concerning infection propensity.
- Management strategies suitable for civilian settings (e.g., antibiotic reliance, minimal debridement) can be disastrous in a war environment.
- Differences in management are influenced by the nature of the wound and the logistical constraints of each scenario.
Conclusions:
- Accurate understanding of missile-tissue biophysics is crucial for effective wound management.
- War and peacetime penetrating wounds require distinct treatment protocols.
- Transposing civilian management strategies to combat settings can lead to adverse outcomes.
Related Concept Videos
Inflammatory Response II: Inflammatory Exudate and Tissue Repair
The typical wound exudate is odorless, transparent, straw-colored, thin, and watery. Exudate, however, can differ depending on the state of wound healing. Likewise, the exudate's...
Phases of Wound Repair
Formation of Blood Clot
In case of deep injuries, trauma to blood vessels results in blood loss. In the meantime, phospholipids released from the ruptured endothelial cellular membrane are converted into arachidonic...
Burn Injuries
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
Healing II: Complications

