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Spectroscopic imaging using concentrically circular echo-planar trajectories in vivo.

Jon K Furuyama¹, Neil E Wilson, M Albert Thomas

¹Department of Radiological Sciences, University of California, Los Angeles, California 90095, USA.

Magnetic Resonance in Medicine

|October 19, 2011

Summary

A new spectroscopic imaging technique, SI-CONCEPT, uses concentric k-space trajectories for faster data acquisition. This method allows for higher spectral bandwidths and reduced excitations, improving magnetic resonance imaging efficiency.

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Area of Science:

Magnetic Resonance Imaging
Spectroscopic Imaging
Neuroimaging

Background:

Standard echo-planar spectroscopic imaging (EPSI) is a common technique for chemical shift imaging.
EPSI faces limitations in slew rates, spectral bandwidth, and magnetic field compatibility.
Developing advanced spectroscopic imaging techniques is crucial for enhanced in vivo metabolite analysis.

Purpose of the Study:

To introduce and evaluate a novel spectroscopic imaging technique called SI-CONCEPT.
To assess the feasibility of using concentric k-space trajectories in spectroscopic imaging.
To compare SI-CONCEPT with standard EPSI regarding data acquisition and spectral quality.

Main Methods:

SI-CONCEPT utilizes concentrically circular k-space trajectories.
Data from concentric rings are regridded into Cartesian space.
A point-resolved spectroscopy sequence localizes the volume of interest before 2D spatial and 1D spectral encoding.
Phantom and in vivo human brain studies were conducted for comparison.

Main Results:

SI-CONCEPT requires significantly reduced slew rates compared to standard EPSI.
The technique enables higher spectral bandwidths, suitable for higher magnetic fields.
Concentric trajectories reduce the number of required excitations by a factor of two for a given resolution.
Spatial profiles and spectra were comparable to standard EPSI.

Conclusions:

SI-CONCEPT offers a viable alternative to standard EPSI, enhancing acquisition efficiency.
The reduced slew rates and excitation requirements make SI-CONCEPT suitable for advanced spectroscopic imaging applications.
Further investigation into potential artifacts and limitations is warranted.